Metabolic Disorders and Cognitive Decline
Conditions
Brief summary
The purpose of the study is to investigate, in healthy middle age subjects, effects of whole grain rye on cognitive functions, mood, and cardiovasculair risk markers
Interventions
OTHERwhole grain
whole grain rye
OTHERreference
white wheat bread
Sponsors
Lund University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
50 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
* healthy * BMI 19-28 * plasma glucose \< 6.1 mmol/L * non smooker
Exclusion criteria
* known metabolic diseases * known gastrointestinal disorders * known cognitive decline.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| cognitive performance | postprandial 0-180 min after breakfast | test of working memory capacity |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| glucose tolerance | 0-180 min after breakfast | postprandial glucose concentrations |
Outcome results
None listed