Effect of Hyaluronidase on Intraocular Pressure

Effect of Hyaluronidase on Intraocular Pressure After Retrobulbar Anaesthesia During Cataract Surgery

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03266406

Enrollment

Registered

2017-08-30

Start date

2017-09-30

Completion date

2018-10-31

Last updated

2017-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intraocular Pressure Low

Brief summary

The aim of this study is to evaluate effect of retrobulbar local anaesthesia after addition of hyaluronidase on IOP during cataract surgery

Interventions

DRUGHyaluronidase

4ml of retrobulbar LA with addition of 15IU/ml hyaluronidase to 2% lidocaine

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

50 Years to 80 Years

Healthy volunteers

Inclusion criteria

* 1-Patients above the age of 50 years. 2-Patients with age related cataract. 3-Normal IOP.

Exclusion criteria

* 1History of trauma. 2-Patients with glaucoma. 3-Previous ocular surgery. 4-Patients with other ocular pathology. 5-Uncontrolled diabetes or hypertension. 6-hypersensitivity to lignocaine. 7-Uncooperative or epileptic patients.

Design outcomes

Primary

Measure	Time frame	Description
reduction in IOP	within 10minutes	reduction of complications of high IOP during surgery

Contacts

Primary ContactEman Yassin

emanyassin08@gmail.com00201004686028

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026