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Evaluate the Link Between the Characteristics of Oral Physiology and the Formation of the Food Bolus During the Consumption of Cereal Products in Elderly People

Evaluation of the Link Between the Characteristics of Oral Physiology and Formation of the Food Bolus During the Consumption of Cereal Products in Elderly People Via a Modelling Approach.

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03227887
Enrollment
20
Registered
2017-07-24
Start date
2016-06-06
Completion date
2016-09-30
Last updated
2017-07-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Old Person

Brief summary

The aim of this study is to understand how foods such as Sponge cake or Brioche are broken down in the mouth. More specifically, investigators wish to evaluate the link between oral physiology (salivation and mastication) and (i) formation of the food bolus during the consumption of Sponge cake or Brioche, that is to say the way in which the food is broken down to be swallowed (ii) mouthfeel during the consumption of Sponge cake or Brioche, meaning the sensations that participant feel when they eat these products. The study will take place at the INRA in Dijon during 7 one-hour sessions spread over 3 months. The first session will allow us to characterise the chewing behaviour of the subjects and their salivation, and will enable us to train them in the instructions for the following sessions. The 6 other sessions will allow us to study the structure of the food bolus while being formed and the mouthfeel of the foods in the project. In the first session: * Two samples of saliva will be taken * A video will be made of subjects eating Sponge cake or Brioche * Subjects will be trained in exercises for the following sessions - this will consist in chewing the study foods and spitting them out on the experimenter's signal. During the 6 other sessions, subjects will be asked to: * Chew one of the study foods and spit it out on the signal of the experimenter. * Evaluate the mouthfeel while eating Sponge cake or Brioche by answering different questions. This test will be done during 4 of the 6 sessions.

Interventions

1. Without stimulation : the 1st will be used to measure the flow of naturally secreted saliva 2. With stimulation: The 2nd will be used to measure the flow and viscosity of the saliva secreted after stimulation

Measure the time taken by the subjects to chew the food and the number of bites they use before swallowing The test will be done twice.

2 tests: 1. Evaluate using a compression test the structure of each bolus to determine their degree of destructuration over time Measure the quantity of the saliva incorporated 2. The bolus will be analysed visually

OTHERMouthfeel

Describe the mouthfeel by answering a paper questionnaire after consumption of the cereal products

Sponsors

Centre Hospitalier Universitaire Dijon
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* persons who have provided written consent * Age ≥ 65 years old * Persons living at home * Persons who can travel independently

Exclusion criteria

* Adults under guardianship * Persons without health insurance cover * Persons in hospital * Persons in institutions * Persons whose Mini-Mental State Examination (MMSE) is \< 24 * Persons requiring enteral or parenteral nutrition * Persons who in the previous 12 months received € 4500 for taking part in clinical trials, including the present study * Persons in a period of exclusion of a previous study * Food allergies (cereal products in particular)

Design outcomes

Primary

MeasureTime frame
Duration of chewing during consumption of cereal productsAt baseline
Frequency of chewing during consumption of cereal productsAt baseline
Rheology testUp to 3 months
Calculation of insalivation ratesUp to 3 months

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026