Postprandial Efficacy of Probiotic Fruit Beverages on Glucose Tolerance and Insulin Resistance

Early Postprandial Efficacy of Probiotic Fruit Beverages on Glucose Tolerance and Insulin Resistance in Healthy Adults

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03159065

Enrollment

Registered

2017-05-18

Start date

2014-09-30

Completion date

2015-01-31

Last updated

2017-05-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postprandial Hyperglycemia

Brief summary

Consumption of polyphenol-rich fruits and vegetables may improve the postprandial glucose and insulin responses and hence promote well-being. It has previously been observed that consumption of a bilberry drink decreases the postprandial insulin demand. In the present study, the impact of probiotic fruit beverages with different polyphenol profiles on the postprandial levels of glucose and insulin, were investigated.

Interventions

OTHERBilberry

Fruit beverage with bilberry and fermented oatmeal

OTHERBlackcurrant

Fruit beverage with blackcurrant and fermented oatmeal

OTHERMango

Fruit beverage with mango and fermented oatmeal

OTHERBeetroot

Fruit beverage with beetroot and fermented oatmeal

OTHERRose hip

Fruit beverage with rose hip and fermented oatmeal

OTHERGlucose drink

A reference glucose drink

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

SCREENING

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* Healthy, not on medication, non-allergic, individuals aged 18-65 years old, having a BMI between 20-30 kg/m2 and also maintaining stable body weight, i.e. less than 5% weight change in the last three months before the study.

Exclusion criteria

Design outcomes

Primary

Measure	Time frame	Description
Efficacy of the study products on the postprandial serum insulin	Incremental area under the curve for serum insulin from 0 min up to 120 min following the ingestion of the study product	The postprandial incremental area under the curve for serum insulin

Secondary

Measure	Time frame	Description
Efficacy of the study products on the postprandial serum glucose	Incremental area under the curve for serum glucose from 0 min up to 120 min following the ingestion of the study product	The postprandial incremental area under the curve for serum glucose

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 24, 2026