Healthy
Conditions
Keywords
meal ingestion, meal composition, postprandial responses, hedonic sensations, homeostatic sensations, new composition
Brief summary
Aim: to determine to what extent meal composition influences postprandial sensations independently of palatability. The postprandial responses to a low-fat (240 Kcal) versus a high-fat (275 Kcal) test meal (150 g humus) with the same physical and organoleptic characteristics (taste, smell, colour, texture, consistency, temperature) will be studied on a cross-over design. The responses to the meals will be tested on 2 different days. Participants (12 non-obese healthy men) will be instructed to eat a standard dinner the day before, to consume a standard breakfast at home after overnight fast, and to report to the laboratory, where the test meal will be administered 3 h after breakfast. Studies will be conducted in a quiet, isolated room with participants sitting on a chair. Perception will be measured at 5 min intervals 10 min before and 20 min after ingestion and at 10 min intervals up to 60 min after the probe meal.
Interventions
OTHERHigh-fat meal
High-fat meal
OTHERLow-fat meal
Low-fat meal with the same physical and organoleptic characteristics as the high-calorie meal.
Sponsors
Hospital Universitari Vall d'Hebron Research Institute
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
MALE
Age
18 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
* non-obese
Exclusion criteria
* history of gastrointestinal symptoms * prior obesity * use of medications * history of anosmia and ageusia * current dieting * alcohol abuse * psychological disorders * eating disorders
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in digestive well-being measured after the test meal | 1 day | Change in average well-being measured by 10 score scales at the end of the test meal. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in satiety measured after the test meal | 1 day | Change in average satiety measured by 10 score scales at the end of the test meal |
| Change in fullness sensation measured after the test meal | 1 day | Change in average fullness measured by 10 score scales at the end of the test meal |
| Change in abdominal discomfort/pain sensation measured after the test meal | 1 day | Change in average abdominal discomfort/pain measured by 10 score scales at the end of the test meal |
| Change in mood measured after the test meal | 1 day | Change in average mood measured by 10 score scales at the end of the test meal. |
Other
| Measure | Time frame | Description |
|---|---|---|
| Meal palatability | 1 day | Meal palatability measured by 10 score scales at the end of the test meal. |
Countries
Spain
Outcome results
None listed