Diabetes Mellitus, Type 2
Conditions
Keywords
Glycemia, Satiety, Insulin, Breakfast, Low glycemic index, High glycemic index
Brief summary
To evaluate the acute effect of a low and high glycemic index breakfast on the glycemic response and satiety in subjects with type 2 diabetes mellitus under intensive insulin therapy.
Interventions
OTHERLow glycemic index
Subjects intake a low glycemic index breakfast
OTHERHigh glycemic index
Subjects intake a high glycemic index breakfast
Sponsors
Universidad de Valparaiso
Study design
Allocation
NON_RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
47 Years to 64 Years
Healthy volunteers
No
Inclusion criteria
* Subjects with type 2 diabetes mellitus diagnosis. * Minimum period of six months under intensive insulin therapy. * Fast insulin prescription before breakfast. * 35 and 70 years of age. * BMI between 25 and 39.9 Kg/m2. * HbA1c less than or equal to 10 % (86mmol/mol) * Menopausal women under hormone replacement therapy
Exclusion criteria
* Pregnant women. * Puerperal women. * Subjects with neurological disease, endocrine disorder no treatment, kidney disease in stage IV or V, cancer, liver disease, chronic obstructive pulmonary disease, human immunodeficiency virus. * Subjects with history of stroke, acute myocardial infarction or gastrointestinal resection.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Glycemia | -15 up to 120 minutes | Glycemia (mg/dL) to -15, 30, 60 and 120 minutes, with respect to breakfast intake |
| Satiety | Up to 120 minutes | Visual Analog Scale (VAS) was applied immediate and tardy postprandial (two hours after eating breakfast). |
Outcome results
None listed