Diabetes Prevention, Obesity Prevention
Conditions
Brief summary
The objectives are to test the acute effects of different bagels containing pulse ingredients on: 1) post-prandial blood glucose, insulin and appetite for two hours, and 2) food intake two hours following consumption of pulse products. The investigators hypothesize that bagels containing pulse ingredients will lead to lower blood glucose, insulin, appetite and food intake responses compared to non-pulse bagels.
Interventions
OTHERControl
Non pulse ingredient bagel
OTHERPea flour
Pulse ingredient bagel
OTHERPea fibre
Pulse ingredient bagel
OTHERPea protein
Pulse ingredient bagel
OTHERPea flour + pea protein
Pulse ingredient bagel
OTHERPea fibre + pea protein
Pulse ingredient bagel
Sponsors
Saskatchewan Pulse Growers
Alberta Pulse Growers
University of Manitoba
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* Normoglycemic (\<5.6 mmol/L) and normotensive (systolic blood pressure \<140 mm Hg and diastolic blood pressure below \< 90 mm Hg) * BMI of 18.5-29.9 kg/m2
Exclusion criteria
* Restrained eaters * Regularly skip breakfast * Smokers * Those who are active (organized activities or athletic training at a high intensity; ≥ 150 min per week of moderate to vigorous physical activity) * Those on medications that may influence study outcomes or have experienced any gastrointestinal related health conditions/surgeries over the past year. * Those unable to walk for an hour continuously
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Plasma Glucose and Insulin Concentrations | 0-200 | Measured in blood using intravenous catheter at 12 time points used to calculate area under curve (AUC). Glucose will be determined by automated methods using Abbot Spectrum CCX Analyzer, and Insulin will be measured by commercially available RIA kits |
| Food Intake | at 120 min | Ad-libitum meal. Food consumed measured by weight |
| Subjective Appetite | 0-200 min | Motivation-to-eat VAS questionnaire used to calculate area under curve (AUC) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Palatability of meal | at 140 mins | Measured by VAS questionnaire |
| Energy/fatigue measured by VAS questionnaire | 0 - 200 mins | Measured by VAS questionnaire at 12 time points, used to calculate area under curve (AUC) |
| Palatability of treatments | at 5 mins | Measured by VAS questionnaire |
| Physical comfort | 0 - 200 min | Measured by VAS questionnaire at 12 time points used to calculate area under curve (AUC) |
Countries
Canada
Outcome results
None listed