Diabetes Prevention, Obesity Prevention
Conditions
Brief summary
The objectives are to test the acute effects of different cereals containing pulse ingredients on: 1) aerobic endurance and substrate oxidation during exercise 2) response of blood glucose, insulin and appetite to an aerobic exercise session, and 3) food intake two hours following the exercise session. The investigators hypothesize that consumption of cereals containing pulse ingredients 60 minutes before exercise will increase aerobic endurance (lower oxygen consumption), decrease carbohydrate oxidation (greater respiratory quotient), and a reduction in lactate production during compared to the same exercise session following the ingestion of a non-pulse food. The investigators also hypothesize that consumption of cereals containing pulse ingredients will lead to lower blood glucose, insulin, appetite and food intake, suggesting lower calorie compensation, following a 60-minute aerobic exercise session compared to the same exercise session following the ingestion of a non-pulse food.
Interventions
OTHERControl
Non pulse extruded cereal
OTHERPea protein
Pulse extruded cereal
OTHERPea Starch
Pulse extruded cereal
Pulse extruded cereal
Pulse extruded cereal
Pulse extruded cereal
Sponsors
Saskatchewan Pulse Growers
Alberta Pulse Growers
University of Manitoba
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* Normoglycemic (\<5.6 mmol/L) and normotensive (systolic blood pressure \<140 mm Hg and diastolic blood pressure below \< 90 mm Hg) * Body Mass Index of 18.5-29.9 kg/m2
Exclusion criteria
* Restrained eaters * Regularly skip breakfast * Smokers * Those on medications that may influence study outcomes or have experienced any gastrointestinal related health conditions/surgeries over the past year * Those who are active (organized activities or athletic training at a high intensity; ≥ 150 minutes per week of moderate to vigorous physical activity) * Those unable to walk for an hour continuously
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Plasma Glucose Concentrations | 0-240 minutes | Measured in blood using intravenous catheter. Glucose will be determined by automated methods using Abbot Spectrum Clinical Chemistry-X Analyzer, |
| Food Intake | at 240 minutes | Ad-libitum meal |
| Subjective Appetite | 0-240 minutes | Motivation-to-eat Visual Analog Scale questionnaire |
| Exercise intensity | 60-120 minutes | Oxygen consumption measured during exercise at 3 time points |
| Insulin concentrations | 0-240 minutes | Measured in blood using intravenous catheter. and Insulin will be measured by commercially available radioimmunoassay (RIA) kits |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Physical comfort measured by Visual Analog Scale questionnaire | 0-240 minutes | Contributions from energy intake |
| Palatability measured by Visual Analog Scale questionnaire | 5 and 260 minutes | Food tasting |
| Energy/fatigue measured by Visual Analog Scale questionnaire | 0 - 240 minutes | Estimate of energy expenditure |
| Heart rate | 60-120 minutes | To monitor exercise intensity and give a measure of fatigue (cardiovascular drift) |
| Substrate Oxidation | 60-120 minutes | Respiratory quotient measured during exercise at 3 time points |
| Lactate concentration | 60-120 minutes | Measured before, during, and after exercise exercise at 3 time points |
Countries
Canada
Outcome results
None listed