Obesity
Conditions
Keywords
Weight Loss, Potatoes, Dietary Meetings, Glycemic Control
Brief summary
The purpose of this study is to test whether diets that contain potatoes and differ in glycemic index/load will be useful in weight loss, blood sugar control and maintaining current body weight.
Detailed description
The study will examine the effect of including potatoes as part of a calorie restricted diet designed to induce weight loss and improve glycemic control in overweight subjects. This is a randomized, treatment-controlled, 3-arm, parallel study. The 3 arms of the study will include dietary manipulation in the free-living setting to include potatoes/potato products frequently in the diet (5-7 days / week). Two diets will be energy-restricted (\ 500 kcal deficit /d) for weight loss and the control diet will be prescribed for weight maintenance. The two energy-restricted diets will include further manipulation, such that, one dietary plan will be a high glycemic index (GI) diet and the other a low glycemic index diet.
Interventions
BEHAVIORALControl
Dietary manipulation in the free-living setting to include potatoes/potato products frequently in the diet (5-7 days / week). The control diet will be prescribed for weight maintenance.
BEHAVIORALLow Glycemic Index
Diets will be energy-restricted (\ 500 kcal deficit /d) for weight loss, will include consumption of 5-7 potatoes/week, and will focus on Low Glycemic Index foods.
BEHAVIORALHigh Glycemic Index
Diets will be energy-restricted (\ 500 kcal deficit /d) for weight loss, will include consumption of 5-7 potatoes/week, and will focus on Low Glycemic Index foods.
Sponsors
University of California, Davis
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Men and women * ≥ 18 years of age who have a body mass index (BMI) of 25 to 35 kg/m2 (inclusive).
Exclusion criteria
* Total cholesterol (TC) not greater than 300 mg/dL, * Fasting triglyceride not greater than 300 mg/dL , * LDL cholesterol (LDL-C) not greater than 180 mg/dL, * Smokers * Female subjects who are pregnant or lactating * Subjects taking any medications that would interfere with outcomes of the study * Subjects with unusual dietary habits (eg., pica) * Subjects who are actively losing weight or trying to lose weight * Subjects who are addicted to drugs or alcohol or who are \< 1 y in recovery program * Subjects who present with significant psychiatric or neurological disturbances * Subjects with known allergy or intolerance to potato products * Subjects with documented atherosclerotic disease, inflammatory disease, diabetes mellitus, uncontrolled hypertension ( 140/90 mm Hg), chronic lung, renal or liver disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Weight Loss | 12 Weeks |
Secondary
| Measure | Time frame |
|---|---|
| Glucose tolerance | 12 Weeks |
| Body composition | 12 weeks |
| Blood Pressure | 12 weeks |
Countries
United States
Outcome results
None listed