Efficacy of Surgical Preparations in Lumbar Spine Surgery

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01105195

Enrollment

100

Registered

2010-04-16

Start date

2010-01-31

Completion date

2010-11-30

Last updated

2010-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infection

Keywords

DuraPrep, ChloraPrep, Lumbar Spine

Brief summary

The purpose of this study is to 1) identify the common bacterial flora found on the skin overlying the lumbar spine, and 2) evaluate the efficacy of readily available skin-preparation solutions in the elimination of bacterial pathogens from the surgical site following skin preparation (DuraPrep versus ChloraPrep).

Interventions

OTHERDuraPrep

DuraPrep is used for skin preparation prior to surgery.

OTHERChloraPrep

ChloraPrep is used for skin preparation prior to surgery.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* All patients undergoing lumbar spine surgery (discectomy, laminectomy, fusion, etc).

Exclusion criteria

* Open wound at the incision site, * Abrasion in the vicinity of the incision site, * An active infection at or near the surgical site, or * An active infection elsewhere in the body.

Design outcomes

Primary

Measure	Time frame	Description
Positive culture results	7 days	Our primary outcome measure is positive aerobic and/or anaerobic cultures reported at 7 days.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026