ChloraPrep

DRUG17 trials

Sponsors

Northwestern University, Solventum US LLC, Sanford Health, Zurex Pharma, Inc., 3M

Conditions

Antimicrobial EffectArthroplasty, Hip ReplacementBacterial ColonizationBacterial Recovery of Skin Flora Post-product ApplicationBacterial Reduction Post-product ApplicationClosed Lower Extremity FractureHealthyInfection

Phase 1

Safety Study to Evaluate the Contact Sensitizing Potential of Topically Applied ZuraPrep™ and ZuraPrep™ Without IPA

CompletedNCT02160587

Zurex Pharma, Inc.Surgical Site Infection

Start: 2014-07-31End: 2014-10-31Updated: 2015-03-17

Safety Study to Evaluate the Cumulative Irritation Potential of Topically Applied ZuraPrep™ and ZuraPrep™ Without IPA

CompletedNCT02160574

Zurex Pharma, Inc.Surgical Site Infection

Start: 2014-06-30End: 2014-09-30Updated: 2014-10-27

Phase 2

Efficacy Study to Evaluate Antimicrobial Effectiveness of ZuraPrep™

TerminatedNCT02221232

Zurex Pharma, Inc.Surgical Site Infection

Start: 2014-08-31End: 2014-10-31Updated: 2016-07-18

Efficacy Study to Evaluate Antimicrobial Effectiveness of ZuraPrep™ (ZX-ZP-0055)

CompletedNCT02296645

Zurex Pharma, Inc.Surgical Site Infection

Start: 2014-11-30End: 2015-01-31Updated: 2016-07-14

In Vivo Preoperative Skin Preparation Persistence Evaluation

CompletedNCT03155178

Solventum US LLCBacterial Recovery of Skin Flora Post-product Application

Start: 2016-12-05End: 2017-04-25Updated: 2024-10-02

Effectiveness of an Antimicrobial Agent for Preoperative Skin Preparation

CompletedNCT03224299

Becton, Dickinson and CompanyPreoperative Skin Preparation

Start: 2017-06-21End: 2017-10-03Updated: 2021-04-23

Phase 3

In-vivo Efficacy Study of Patient Preoperative Preps

TerminatedNCT01968356

Solventum US LLCSkin Flora Bacterial Reduction Post-product Application

Start: 2013-10-31End: 2014-01-31Updated: 2024-10-02

In Vivo Efficacy Study of Patient Preoperative Preps

CompletedNCT02203591

3MBacterial Reduction Post-product Application

Start: 2014-07-31End: 2015-03-31Updated: 2020-11-23

Clinical Evaluation of Patient Preoperative Prep

CompletedNCT02831816

Zurex Pharma, Inc.Surgical Skin Preparation

Start: 2016-08-03End: 2017-08-03Updated: 2021-07-16

In-vivo Efficacy of Patient Preoperative Prep

CompletedNCT02831998

Zurex Pharma, Inc.Surgical Skin Preparation

Start: 2016-07-27End: 2017-04-09Updated: 2023-02-08

An Evaluation of the Efficacy of HEXI-PREP by Clinell Wipes

CompletedNCT03417661

Gama Healthcare Ltd.Antimicrobial Effect

Start: 2018-06-29End: 2019-09-18Updated: 2020-07-22

In-vivo Efficacy of Patient Preoperative Prep, ZuraPrep (ZP)

CompletedNCT03782103

Zurex Pharma, Inc.Surgical Skin Preparation

Start: 2019-01-25End: 2019-09-26Updated: 2023-02-08

Phase 4

Compare Effect of Surgical Antiseptic Preparations on Incise Drape Adhesion to Skin

CompletedNCT01290978

Solventum US LLCHealthy

Start: 2010-02-28End: 2010-03-31Updated: 2024-10-02

Study on the Reapplication of Chloraprep After Lower Extremity Surgery and Prior to Dressing Application

Sanford HealthBacterial Colonization, Lower Extremity Surgery, Surgical Antiseptic +1

Start: 2014-02-28Target: 140Updated: 2014-02-19

Pre-operative Alcohol Skin Solutions in Fractured Extremities

CompletedNCT03523962

University of Maryland, BaltimoreClosed Lower Extremity Fracture, Open Appendicular Fracture, Pelvic Fracture +2

Start: 2018-08-21End: 2024-02-02Updated: 2024-10-04

Unknown Phase

Efficacy of Surgical Preparations in Lumbar Spine Surgery

CompletedNCT01105195

Northwestern UniversityInfection

Start: 2010-01-31End: 2010-11-30Target: 100Updated: 2010-11-17

Efficacy of Surgical Skin Preparation Solutions in Hip Arthroplasty Surgery

CompletedNCT03393819

Lakehead UniversityArthroplasty, Hip Replacement, Infection, Postoperative Wound

Start: 2014-10-29End: 2016-04-06Updated: 2019-07-01

Related Papers

Skin Antisepsis before Surgical Fixation of Extremity Fractures

New England Journal of Medicine2024-01-3156 citations

The impact of heterotopic ossification prophylaxis after surgical fixation of acetabular fractures: national treatment patterns and related outcomes.

2023-03-062 citations

Cluster identification, selection, and description in cluster randomized crossover trials: the PREP-IT trials.

2020-08-125 citations

Effectiveness of Iodophor vs Chlorhexidine Solutions for Surgical Site Infections and Unplanned Reoperations for Patients Who Underwent Fracture Repair

JAMA Network Open2020-04-0729 citations

Antiseptic efficacy of an innovative perioperative surgical skin preparation: A confirmatory FDA phase 3 analysis

Infection Control and Hospital Epidemiology2020-03-056 citations