Blood Glucose, Postprandial
Conditions
Keywords
viscous, fibre, polysaccharide, blood glucose, postprandial
Brief summary
Reductions of postprandial glucose levels have been demonstrated previously with the addition of a novel viscous polysaccharide (NVP) to a glucose drink and standard white bread. This study explores whether these reductions are sustained when NVP is added to a range of commonly consumed foods.
Detailed description
Recently, a commercial novel viscous polysaccharide (NVP)complex has been developed which is marketed in both the USA and Canada under the trade name PGX® (PolyGlycopleX) (InovoBiologic Inc, Calgary, AB, Canada). This complex consists of three viscous non starch polysaccharides which are processed using proprietary technology (EnviroSimplex®) to produce compressed granules which delays the onset of viscosity and increases palatability of the fiber when added to food. Previously, this fibre was shown to lower postprandial glucose levels in a dose responsive manner when mixed with a glucose drink and sprinkled onto a standard white bread demonstrating that the processing did not interfere with the effectiveness of the fiber. From this study the reduction in GI was calculated to be 7 units per gram of NVP when added to a solid food, however it is not known whether this relationship would be maintained when the NVP was added to a range of commonly eaten foods. This study therefore evaluates the effect of the addition or incorporation of NVP into a range of foods on postprandial glycemia and whether the reductions in glycemic index could be predicted using.
Interventions
2.5 grams of PGX
Sponsors
Study design
Eligibility
Inclusion criteria
* healthy individuals * 18-75 years old * BMI less than 35 kg/m2
Exclusion criteria
* Medications influencing gastrointestinal function * Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Relative Blood glucose response of food with and without NVP | Acute blood glucose response measured at 0, 15,30,45,60,90 and 120 min |
Countries
Canada