Effect of Escalating Doses of a Novel Viscous Polysaccharide on Postprandial Glycemia

Effect of Adding Escalating Doses of a Novel Highly Viscous Polysaccharide to Either a Liquid or a Solid Test Meal on Post Prandial Glycemia in Healthy Subjects: Determination of the Glycemic Reduction Index Potential (GRIP)

Status

Completed

Phases

Phase 2Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00801814

Enrollment

Registered

2008-12-04

Start date

2006-04-30

Completion date

2006-08-31

Last updated

2008-12-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood Glucose, Postprandial

Keywords

viscous, fibre, polysaccharide, blood glucose, post prandial

Brief summary

To determine palatability and extent to which escalating doses of a novel highly viscous polysaccharide \[NVP\] reduces postprandial glycemia when added to a liquid and a solid meal.

Interventions

DIETARY_SUPPLEMENTPolyGlycopleX (PG)

5.0 grams of PGX

DIETARY_SUPPLEMENTPolyGlycopleX

7.5 grams of PGX

DIETARY_SUPPLEMENTControl

0g of PGX

DIETARY_SUPPLEMENTSecond Control

0g of PGX

DIETARY_SUPPLEMENTPolyGlycopleX (PGX)

2.5 grams of PGX

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Yes

Inclusion criteria

* healthy individuals * 18-75 years old * BMI less than 35 kg/m2

Exclusion criteria

* Medications influencing gastrointestinal function * Pregnancy

Design outcomes

Primary

Measure	Time frame
postprandial glycemia	Acute study measuring postprandial glucose levels over 2 hours

Secondary

Measure	Time frame
The glucose reduction index potential (GRIP). The GRIP factor is the reduction in glycemic index units per gram of fiber.	Data analysis

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026