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Efficacy of Low-Intensity Pulsed Ultrasound in Protecting Skeletal Muscle Structure and Function in Sepsis Patients: An Evaluation Based on Ultrasound and Surface Electromyography

Efficacy of Low-Intensity Pulsed Ultrasound in Protecting Skeletal Muscle Structure and Function in Sepsis Patients: An Evaluation Based on Ultrasound and Surface Electromyography

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600120044
Enrollment
Unknown
Registered
2026-03-09
Start date
2026-03-16
Completion date
Unknown
Last updated
2026-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

Intervention group:Low-intensity pulsed ultrasound

Sponsors

The Second Xiangya Hospital, Central South University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Aged older than 18 years, regardless of gender; 2.Met the diagnostic criteria for Sepsis-3.0; 3.Expected length of stay in the intensive care unit of greater than 7 days at the time of enrollment; 4.Within 48 hours of the diagnosis of sepsis;

Exclusion criteria

Exclusion criteria: 1.Presence of open wounds, severe burns, cellulitis, or unoperated lower limb fractures in the tibialis anterior muscle region; 2.Presence of deep vein thrombosis in the lower extremities; 3.Implantation with a cardiac pacemaker or other implantable electronic devices; 4.Women who are pregnant or lactating; 5.Allergy to medical couplants (ultrasound gel);

Design outcomes

Primary

MeasureTime frame
Muscle Thickness of Tibialis Anterior;Cross-Sectional Area (CSA) of Tibialis Anterior;Root Mean Square;Integrated EMG (iEMG);

Secondary

MeasureTime frame
ICU Length of Stay and ICU Mortality;Manual Muscle Testing;M-wave Area;local skin reaction;M-wave Amplitude;ICU Mobility Scale;

Countries

China

Contacts

Public ContactXinwei Liu

The Second Xiangya Hospital, Central South University

1109627843@qq.com+86 731 85295170

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 20, 2026