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Canceled by the investigator. The effect of frontal infiltration and intravenous dexmedetomidine on the stress factors and haemodynamic response to skull-pin placement for craniotomy

The effect of frontal infiltration and intravenous dexmedetomidine on the stress factors and haemodynamic response to skull-pin placement for craniotomy

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400079492
Enrollment
Unknown
Registered
2024-01-04
Start date
2024-01-15
Completion date
Unknown
Last updated
2024-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

trigeminal neuralgia

Interventions

Sponsors

Guangxi Hospital Division of The First Affiliated Hospital, Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing elective craniotomys with kull-pin placement; 2, Patient obtained written informed consent; 3, Age between 18 and 60 years old; 4, ASA classification I or II.

Exclusion criteria

Exclusion criteria: Patients with proven or suspected allergy to bupivacaine, a history of coronary artery disease, patients who had received antihypertensive therapy or who had uncontrolled hypertension, arrhythmia, coagulopathies or diabetes mellitus, with aneurysm or any other cerebrovascular disorder, and patients with raised ICP or a history of brain trauma were excluded from the study.

Design outcomes

Primary

MeasureTime frame
adrenocorticotropic hormone;serum cortisol;blood glucose;

Secondary

MeasureTime frame
Heart rate;blood pressure;

Countries

China

Contacts

Public ContactKecheng Huang

Guangxi Hospital Division of The First Affiliated Hospital, Sun Yat-sen University

119737479@qq.com+86 173 0771 1362

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026