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objective to evaluate the effectiveness of fluorescent imaging on the surface of oral lesions with MET-targeted probe of operation

objective to evaluate the effectiveness of fluorescent imaging on the surface of oral lesions with MET-targeted probe of operation

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100042895
Enrollment
Unknown
Registered
2021-01-31
Start date
2021-03-03
Completion date
Unknown
Last updated
2021-05-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral squamous cell carcinoma

Interventions

Gold Standard:Postoperative pathological section verification of oral lesions.
Index test:Mesenchymal&#32
(MET)&#32
in&#32
imaging&#32
of&#32

Sponsors

Shanghai Ninth People's Hospital, Shanghai Jiaotong University, School of Medcine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1) Patients aged 18-70 years; 2) The patients suspected of oral squamous cell carcinoma by clinical and conventional imaging diagnosis and with surgical indications; 3) The subjects voluntarily participated in the clinical trial and signed the informed consent.

Exclusion criteria

Exclusion criteria: 1) He had been operated on oral diseases; 2) He had received radiotherapy or neoadjuvant chemotherapy for oral squamous cell carcinoma; 3) Patients with ICG and iodine allergy; 4) Participate in clinical trials of other drugs within three months; 5) The researcher thinks that it is not suitable to participate in this clinical.

Design outcomes

Primary

MeasureTime frame
NIR imaging;SEN, SPE, ACC, AUC of ROC;

Countries

China

Contacts

Public ContactTao Xiaofeng

Shanghai Ninth People's Hospital, Shanghai Jiaotong University, School of Medcine

cjr.taoxiaofeng@vip.163.com+86 21-23271699

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026