Prostate Cancer
Conditions
Interventions
Gold Standard:Pathological diagnosis of prostate cancer: Pathological findings from a biopsy of the prostate, or prostate cancer found after a transurethral resection of the prostate
serum 
(PSA) 
and 
Neuron 
Enolase 
(NSE)
 
Multiparameter 
magnetic 
resonance 
imaging 
Sponsors
the Second Hospital of Tianjin Medical University
Eligibility
Sex/Gender
Male
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: The clinical diagnosis of prostate cancer is suspected in all prostate disease patients who have abnormal serum PSA test, or abnormal DRE, or abnormal TRUS or MRI abnormal signal, which is consistent with the indication of the first prostate biopsy patients who meet the following criteria can be enrolled into the group: 1. Aged 18 to 80 years; 2. No significant cardiopulmonary dysfunction, no serious chronic diseases such as diabetes; ECOG Score 0-1; 3. Patients can be examined with diffusion-weighted imaging (DWI) and T2-weighted imaging (T2WI), and the PI-RADS score >=4; 4. Clinical staging of cT1-3bN0-1M0; 5. The patient does not want to receive a prostate biopsy; 6. The patient consented to a 68Ga-PSMA-PETCT examination and specific visualization of the prostate cancer site; 7. The PSMA-PETCT report was localized prostate cancer without distant lymph node, bone and visceral metastasis; 8. No neoadjuvant endocrine therapy or chemotherapy is required depending on the clinical stage, and is willing to undergo radical prostatectomy and standard lymphadenectomy; 9. The patient has no history of other organ malignancies; 10. The patient voluntarily signs an informed consent form.
Exclusion criteria
Exclusion criteria: Patients with prostate disease who did not meet the criteria for inclusion in the study, or who the researchers considered unsuitable for inclusion in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mp-MRI;Ga68-PSMA-PETCT; | — |
Countries
China
Contacts
Public ContactLiu Ranlu
Department of Urology, the Second Hospital of Tianjin Medical University
Outcome results
None listed