Hip fracture in the elderly and distal femoral fracture in the elderly
Conditions
Interventions
experimental group 2:EPO, Fe
experimental group 3:TXA??EPO???
Sponsors
Chongqing General Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Admission combined with imaging examination (CR, CT, MRI, etc.) was confirmed as the first fresh unilateral femoral neck, intertrochanteric fracture or distal femoral fracture, aged >=65 years, injury time <=6h.
Exclusion criteria
Exclusion criteria: Time of injury: > 6h; Open fractures or hemorrhagic wounds in other parts of the body or hemorrhagic diseases in other parts of the body (such as gastrointestinal bleeding); Combined with other fresh fractures; Patients with previous clotting dysfunction; Those who were admitted to hospital and found thrombosis in deep vein of lower extremity by vascular color ultrasound, or had a history of thromboembolism; Pulmonary infection or other site infection, which cannot be effectively controlled; Electrolyte disturbance and abnormal blood volume; Patients with serious diseases such as heart, liver, kidney, brain and lung; It has always been clear that patients who are allergic to tranexamic acid or allergic constitution should be combined with the patient's general condition before the application of tranexamic acid, referring to the instructions of tranexamic acid, RHU-EPo, iron sucrose or The Chinese Pharmacopoeia. If there are adverse reactions, they should be dealt with in time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HGB;Hct;Hidden Blood loss; | — |
Secondary
| Measure | Time frame |
|---|---|
| Proportion of transfused patients;The incidence of deep vein thrombosis and pulmonary embolism; | — |
Countries
China
Contacts
Public ContactHuixu Ma
Chongqing General Hospital
Outcome results
None listed