Vocal Cord Polyps
Conditions
Interventions
Group 1:THRIVE
Group 2:tracheal intubation
Sponsors
Eye & ENT Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 60 years; 2. ASA I~II; 3. Plan for microlaryngoscopic surgery under general anesthesia; 4. Anticipated surgery duration shorter than 20 min.
Exclusion criteria
Exclusion criteria: 1. Nasal obstruction; 2. Obstructive sleep apnoea; 3. Tracheal stenosis or tumor; 4. Known or predicted difficult intubation; 5. Known or predicted difficult mask ventilation; 6. Known or suspected cervical spine instability; 7. Skull base defects; 8. Coronary heart disease; 9. Significantly decreased myocardial function (ejection fraction < 50%); 10. Abnormal cardiac rhythm and conduction abnormalities, except for patients with isolated, asymptomatic premature atrial and ventricular contractions; 11. Cerebrovascular disease, such as history of cerebrovascular accidents (CVAs) and transient ischemic attacks (TIAs); 12. Stenosis of the carotid or vertebral arteries; 13. Significant peripheral vascular disease, as manifested by intermittent claudication; 14. History or symptoms of increased intracranial pressure or reduced intracranial compliance (e.g. headaches, nausea and vomiting, visual changes, mental changes); 15. Hypertension, over 180/110mmHg; 16. Pulmonary hypertension; 17. Chronic obstructive or restrictive lung diseases, chronic hypoxia or hypercapnia, or baseline room air SpO2 < 95%; 18. Recent upper respiratory tract infection; 19. Asthma; 20. Neuromuscular disorders; 21. Electrolyte (K+, Ca2+) abnormalities; 22. Obesity with BMI above 30 kg/m2; 23. Severe or poorly controlled gastroesophageal reflux disease; 24. Patients with full stomach; 25. Pregnant or breastfeeding patients; 26. Anaemia; 27. Usage of surgery instruments with high risk of airway fire; 28. Allergy to any agent used in the study; 29. Patient refuse to participate in the study; 30. Patients who do not understand Mandarin or mentally handicapped.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of emergence;PACU stay duration; | — |
Secondary
| Measure | Time frame |
|---|---|
| time of anesthesia;time of ETT/LMA removal;soar throat score; | — |
Countries
China
Contacts
Public ContactLi Wenxian
Eye & ENT Hospital, Fudan University
Outcome results
None listed