hip and knee joint disease
Conditions
Interventions
Gold Standard:The definition and diagnostic criteria introduced by the Musculoskeletal Infection Society (MSIS)
and 
 
Serum 
FDP 
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Primary unilateral total knee arthroplasty (TKA) for severe osteoarthritis of the knee, and primary unilateral total hip arthroplasty (THA) for osteoarthritis of the hip, dysplasia of the hip (DDH) and necrosis of the femoral head (40 cases);40 patients underwent primary total joint arthroplasty due to inflammatory diseases such as rheumatoid arthritis and ankylosing spondylitis. 2. Patients undergoing joint revision for non-infectious reasons;Patients undergoing surgical treatment for infection (primary/secondary surgery/debridement and drainage); Patients who underwent a second surgery (temporary prosthesis removal, total hip/knee revision) due to infection; Of these, 59 were infected and 47 were non-infected.
Exclusion criteria
Exclusion criteria: 1. Patients who may refuse to participate in this study; 2. Patients with deep vein thrombosis (DVT); 3. Patients with oral anticoagulants or antiplatelet drugs; 4. Patients with hemophilia A or B; 5. Patients who were given antibiotics 2 weeks before surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma FDP, D-dimer and fibrinogen;Serum FDP and D-dimer;Testing and culture of joint fluid;ESR, CRP and IL-6; | — |
Countries
China
Contacts
Public ContactZongke Zhou
West China Hospital, Sichuan University
Outcome results
None listed