sepsis
Conditions
Interventions
Normal control group:Nil
Sponsors
Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria of the sepsis group: 1. Diagnosis of sepsis; 2. Aged between 18-65 years old, regardless of gender; 3. Hospitalization time> 24 hours; 4. The patients volunteered to participate in the clinical study and signed the informed consent. Inclusion criteria of healthy volunteers: 30 healthy volunteers who had physical examination in our hospital during the same period were taken as control.
Exclusion criteria
Exclusion criteria: 1. Dying condition (estimated survival time < 24 hours); 2. Previous history of diabetes; 3. Previous malignant tumor; 4. Previous neurodegenerative disease (Parkinson's disease); 5. Pregnant patients; 6. Participants in other clinical trials within 1 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood sestrin2; | — |
Secondary
| Measure | Time frame |
|---|---|
| SOFA scores;GCS scores;APACHEII scores;high-sensitivity C-reactive protein;Procalcitonin;Lactic Acid;Blood Glucose;High-Sensitivity Cardiac Troponin;NT-proBNP;White Blood Cell Count;Hemoglobin;Hematocrit;Platelet Count;Alanine Aminotransferase;Aspartate Aminotransferase;Total Bilirubin;Direct Bilirubin;Indirect Bilirubin;Lactate Dehydrogenase;Urea Nitrogen;Creatinine;Arterial blood PH;Oxygen Partial Pressure;partial pressure of carbon dioxide;bicarbonate ion-;D-dimer;International normalized ratio;Fibrinogen;28-day survival;Ventilator use days;ICU hospital stay;Total days in hospital; | — |
Countries
China
Contacts
Public Contactwei zhu
Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology
Outcome results
None listed