Stroke
Conditions
Sponsors
Chinese Medicine Hospital of Zhejiang Province
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with aged >=18 years; 2. Patients with unilateral cerebral hemisphere stroke confirmed by MRI for the first time; 3. According to the time from onset (symptom appearance) to admission time > 2W, the patients were divided into subacute stage: 2W 6m; 4. Patients with hemiplegia or hemiplegia with unilateral upper limb motor function impairment; 5. The patients or their guardians participated in the study voluntarily and informed consent was signed.
Exclusion criteria
Exclusion criteria: 1. Patients with brainstem or cerebellar stroke; 2. Patients with electronic or ferromagnetic implants in the head, neck or chest (such as intracranial shunt, artificial heart valve, pacemaker, drug pump, etc.); 3. Patients with metal fragments in their eyes or head; 4. Patients with epilepsy or epileptic seizure history; 5. Patients with other contraindications to TMS and MRI; 6. Patients with NIHSS score > 20; 7. Patients with severe neurodegenerative diseases (such as Parkinson's disease and Alzheimer's disease); 8. Patients with severe neuroinflammatory diseases (such as multiple sclerosis); 9. Patients with malignant tumor involving central nervous system; 10. Patients with serious mental and psychological diseases; 11. Patients with bilateral hemiplegia or M1 or corticospinal tract infarction in the same hemisphere as hemiplegia; 12. Patients with known surgical or traumatic brain injury; 13. Patients with increased intracranial pressure; 14. Patients with severe cardiac insufficiency; 15. Pregnant or lactating women; 16. Patients with uncontrollable diabetes or hypertension; 17. Patients with severe cognitive or communication impairment who cannot cooperate with treatment or assessment; 18. Patients who are considered unsuitable for the clinical study by the physician in charge.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mRs;ARAT;FMA-UE;ADL; | — |
Countries
China
Contacts
Public ContactMao Yajun
Chinese Medicine Hospital of Zhejiang Province
Outcome results
None listed