cerebral arteriovenous malformation
Conditions
Interventions
A:Fractional partial embolization according to the circumstances
Onyx was injected into two microcatheters of large blood supply arteries according to double-catheter technique, and blood pressure was strictly controlled after operation.
Intraoperative control hypotension was adopted.Blood pressure was strictly controlled after operation.
Sponsors
The First Affiliated Hospital of PLA Navy Medical University
Eligibility
Sex/Gender
All
Age
13 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. BAVM patients; 2. Aged >= 13 and <= 60 years; 3. The informed consent is signed by the patient himself or his legal guardian or representative.
Exclusion criteria
Exclusion criteria: 1. AVM has a history of embolization, radiation therapy or partial resection. 2. MRS >= 3 points due to intracranial hemorrhage or neurological dysfunction before treatment; 3. Radiologically confirmed complicated with ruptured aneurysm; 4. AVM is too diffuse;Platelet count 1.4, or TP or ATPP increased; 5. Any irreversible clotting disorder or known clotting disorder; 6. Patients requiring long-term anticoagulation; 7. Premenopausal women with positive urine or plasma pregnancy tests (no recorded history of surgical sterilization); 8. Major concomitant diseases such as liver, kidney, gastrointestinal, respiratory, cardiovascular, endocrine, immune and hematological diseases that are subject to imaging safety assessment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Immediate embolization rate after the last endovascular treatment;The vascular malformation occlusion rate was followed up 2 years after operation.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cerebral hemorrhage and ischemic events within one week after the end of the last embolization were included;Intracerebral hemorrhage during clinical follow-up from 1 week after the last embolization to 2 years;MRS scores were obtained during the last clinical follow-up 2 years after surgery; | — |
Countries
China
Contacts
Public ContactQiang Li
The PLA Naval Medical University
Outcome results
None listed