cerebral arteriovenous malformation
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. BAVM patients; 2. Agef 13 to 60 years; 3. The informed consent is signed by the patient himself or his legal guardian or representative.
Exclusion criteria
Exclusion criteria: 1. AVM has a history of embolization, radiation therapy or partial resection; 2. MRS >=3 points due to intracranial hemorrhage or neurological dysfunction before treatment; 3. Radiologically confirmed complicated with ruptured aneurysm; 4. AVM is too diffuse; 5. Platelet count 1.4, or TP or ATPP increased; 6. Any irreversible clotting disorder or known clotting disorder; 7. Patients requiring long-term anticoagulation;Premenopausal women with positive urine or plasma pregnancy tests (no recorded history of surgical sterilization); 8. Major concomitant diseases such as liver, kidney, gastrointestinal, respiratory, cardiovascular, endocrine, immune and hematological diseases that are subject to imaging safety assessment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A. Immediate embolization rate after the last endovascular treatment and B. Vascular malformation occlusion rate following 2 years after the operation.; | — |
Secondary
| Measure | Time frame |
|---|---|
| A. Cerebral hemorrhage and ischemic events within one week after the last embolization; B. Cerebral hemorrhage events during clinical follow-up from 1 week after the last embolization to 2 years; C. MRS in the last clinical follow-up 2 years after the operation.; | — |
Contacts
The First Affiliated Hospital of PLA Navy Medical University