colorectal cancer with liver metastasis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Subjects were required to meet all of the following criteria to be eligible for the study: The age ranged from 18 to 80 years old; Liver metastasis was confirmed by pathological diagnosis; Complete resection of primary and metastatic colorectal cancer (R0); The general condition of the patients after operation was allowed to receive chemotherapy; The expected survival time was more than 6 months; There are enough surgical or biopsy specimens for gene detection; Subjects (or their legal representatives / guardians) must sign informed consent to indicate that they understand the purpose of the study, understand the necessary procedures for the study, and are willing to participate in the study.
Exclusion criteria
Exclusion criteria: Those with one or more of the following are not eligible for this study: Active bleeding with clinical significance; Alcoholism or drug addiction; Important organ failure or other serious diseases, including clinical related coronary artery disease, cardiovascular disease or myocardial infarction, congestive heart failure, unstable angina pectoris, obvious pericardial effusion or unstable arrhythmia within 6 months before enrollment; Severe neurological or psychiatric history; severe infection; active disseminated intravascular coagulation or other accompanying diseases that, according to the investigator's judgment, seriously endanger the safety of the patient or affect the patient's completion of the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ctDNA; | — |
Countries
China
Contacts
Fudan University Shanghai Cancer Center