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Prospective randomized controlled study of percutaneous drainage versus percutaneous endoscopic pancreatic necrotic tissue removal in the treatment of infectious pancreatic necrosis

Prospective randomized controlled study of percutaneous drainage versus percutaneous endoscopic pancreatic necrotic tissue removal in the treatment of infectious pancreatic necrosis

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000037246
Enrollment
Unknown
Registered
2020-08-27
Start date
2020-10-01
Completion date
Unknown
Last updated
2020-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute pancreatitis

Interventions

B:percutaneous endoscopic necrosectomy

Sponsors

The First Affiliated Hospital of Naval Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1) Age: 18-70 years old, male or female 2) The patient was diagnosed as acute pancreatitis complicated with peripancreatic infection (according to the Chinese guidelines for the diagnosis and treatment of acute pancreatitis (2019, Shenyang)). Pus accumulated in the pancreas or around the pancreas, and the peripheral wall was fibrous capsule. Enhanced CT showed bubble sign. The fine needle aspiration was positive for bacterial or fungal culture. 3) Pancreatic abscess has a percutaneous puncture path on CT, which can be used in patients with PCD.

Exclusion criteria

Exclusion criteria: 1) The patients could not tolerate anesthesia or vital signs could not accept percutaneous endoscopic debridement; 2) Coagulation mechanism is abnormal, there is a risk of intraoperative bleeding; 3) Emergency surgical debridement is needed; 4) Endoscopic debridement was performed via stomach; 5) Those who have received other minimally invasive interventional therapy for IPN; 6) The patients were lost to follow-up after operation.

Design outcomes

Primary

MeasureTime frame
The time taken to reduce the necrotic cavity by half;Time for complete closure of necrotic cavity; Cure rate of peripancreatic abscess;Length of stay;

Secondary

MeasureTime frame
Conversion rate to open surgery;Mortality;Incidence of organ failure;Incidence of complications;PEN times;Medical expenses;

Countries

China

Contacts

Public ContactYanBo Zeng

The First Affiliated Hospital of Naval Medical University

yanboz2008@163.com+86 13816023312

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026