Atrial Fibrillaton
Conditions
Interventions
experimental group:mitral isthmus liner ablation plus PVI
control group:PVI
Sponsors
Shanghai General Hospital
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 30 to 80 years ; 2. AF lasting 6 months to 5 years; Two random electrocardiograms and one 24h holter in the half year before enrollment indicate atrial fibrillation.Atrial fibrillation was detected preoperatively. 3. Agree and sign informed consent; 4. Patients must be willing and able to comply with all peri-ablation and follow-up requirements.
Exclusion criteria
Exclusion criteria: 1. Atrial fibrillation caused by reversible causes, such as untreated hyperthyroidism; 2. Previous surgery due to atrial fibrillation, whether cardiac surgery or percutaneous interventional procedure (including surgical maze operation, catheter ablation and left atrial appendage occlusion procedure, etc.); 3. Severe organic heart disease (such as severe mitral stenosis or reflux, severe aortic valve stenosis or reflux, hypertrophic obstructive cardiomyopathy, dilated cardiomyopathy, restrictive cardiomyopathy, etc.); 4. Existence of thrombus and tumor in the atrium; 5. The anteroposterior diameter of left atrium > 55mm (2D echocardiography, long axis view beside sternum); 6. Contra-indication to heparin or oral anticoagulant therapy; 7. Creatinine clearance < 30ml/min; 8. Pregnant women; 9. Novel Coronavirus infected patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Freedom from documented AF/AT episodes > 30 seconds at 12 months after one ablation procedure without antiarrhythmic medications, 3 months after ablation is a blank period.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Procedure time;Fluoroscopy time;Ablation time;Freedom from documented AF episodes > 30 seconds at 12 months after one ablation procedure without antiarrhythmic medications;Freedom from documented AT episodes > 30 seconds at 12 months after one ablation procedure without antiarrhythmic medications;Relationship of acute AF termination to long-term procedural outcome; | — |
Countries
China
Contacts
Public ContactShaowen Liu
Shanghai General Hospital
Outcome results
None listed