The predictive value of urinary cell cycle arrest factor on early recovery of renal function in patients with acute renal injury after thoracic and abdominal surgery

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000031604

Enrollment

Unknown

Registered

2020-04-05

Start date

2020-04-15

Completion date

Unknown

Last updated

2020-04-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Kidney Injury

Interventions

Gold Standard:clinical outcomes

Index test:urinary&#32

cell&#32

cycle&#32

arrest&#32

factor&#32

([TIMP-2]*[IGFBP7])

Eligibility

Sex/Gender

All

Age

18 Years to 95 Years

Inclusion criteria

Inclusion criteria: 1. Adult with thoracic and abdominal surgery, aged above 18 years 2. Patients who met AKI diagnostic criteria in KDIGO guidelines 3. Patient who obtained informed consent

Exclusion criteria

Exclusion criteria: 1. Patients who already had AKI before admitted to SICU; 2. Patients who were collected insufficient urine sample; 3. Patients who already had chronic kidney disease before admitted to SICU; 4. Patients who were expected survival less than 48 hours.

Design outcomes

Primary

Measure	Time frame
Incidence of early recovery of renal function in newly diagnosed AKI patients after thoracic and abdominal surgery;SEN, SPE, ACC, AUC of ROC;	—

Secondary

Measure	Time frame
All-cause mortality of 28 days in newly AKI patients after thoracic and abdominal surgery;	—

Countries

China

Contacts

Public ContactLi Wenxiong

Beijing Chaoyang Hospital, Capital Medical University

lwx7115@sina.com+86 13601097813

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026