Recurrent Glioblastoma
Conditions
Brief summary
Immunological responsiveness of blood T cells as determined by interferon-gamma and multi-cytokine responses towards tumor lysate-loaded DC during vaccination.
Detailed description
Feasibility (production and application of therapeutics)., Safety based on the frequency and severity of AE with toxicity graded according to the National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE)., Survival based on overall and progression-free survival (according to modified Response Assessment in Neuro-Oncology (RANO) criteria) at six months after surgery.
Interventions
Sponsors
Heinrich-Heine-Universitaet Duesseldorf
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Immunological responsiveness of blood T cells as determined by interferon-gamma and multi-cytokine responses towards tumor lysate-loaded DC during vaccination. | — |
Secondary
| Measure | Time frame |
|---|---|
| Feasibility (production and application of therapeutics)., Safety based on the frequency and severity of AE with toxicity graded according to the National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE)., Survival based on overall and progression-free survival (according to modified Response Assessment in Neuro-Oncology (RANO) criteria) at six months after surgery. | — |
Outcome results
None listed