Autologous

DRUG4 trials

Sponsors

Heinrich-Heine-Universitaet Duesseldorf, Fondazione Policlinico Universitario Campus Bio-medico In Forma A Bbreviata Fon, London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Conditions

Diabetes MellitusNon-alcoholic Fatty Liver DiseaseRecurrent Glioblastomalow back painnewly diagnosed glioblastoma

Phase 1

Transplantation of Microbes for Treatment of Metabolic Syndrome & NAFLD

CompletedNCT02496390

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sDiabetes Mellitus, Non-alcoholic Fatty Liver Disease

Start: 2016-06-30End: 2018-12-31Updated: 2018-12-11

Synergism of dendritic cell vaccination and anti-PD-L1 immune check-point blockade to sensitize recurrent glioblastoma to anti-tumoral immunity

WithdrawnCTIS2026-525397-19-00

Heinrich-Heine-Universitaet DuesseldorfRecurrent Glioblastoma

Target: 6Updated: 2026-08-20

Phase 2

Phase II trial of vaccination with lysate-loaded, mature dendritic cells integrated into standard radiochemotherapy in newly diagnosed glioblastoma

Active, not recruitingCTIS2024-514820-18-00

Heinrich-Heine-Universitaet Duesseldorfnewly diagnosed glioblastoma

Start: 2018-03-07Target: 136Updated: 2025-10-10

Intervertebral Disc REgeneration mediated by Autologous Mesenchymal stem/stromal cells intradiscal injection: a phase IIB randomized clinical trial

CompletedCTIS2024-519112-14-00

Fondazione Policlinico Universitario Campus Bio-medico In Forma A Bbreviata Fonlow back pain

Start: 2025-02-13End: 2025-10-31Target: 52Updated: 2025-11-20

Related Papers

Unraveling the Gut-Liver-Brain Axis: Microbiome, Inflammation, and Emerging Therapeutic Approaches.

2025-06-186 citations