Colonization by methicillin-resistant S. aureus and gut microbiota in users of pre-exposure prophylaxis (PrEP) and people living with HIV (PLHIV) with STIs.
Conditions
Brief summary
to assess the prevalence of nasal colonization by doxycycline-resistant S. aureus strains
Detailed description
To assess differences in the composition of the baseline gut microbiota and at month 12, To assess the development of resistance in the gut microbiota, To assess the prevalence of infections caused by T. pallidum, C. trachomatis, and N. gonorrhoeae, and doxycycline-resistant C. trachomatis.
Interventions
DRUGDOXYCYCLINE
DRUGBiktarvy 30 mg/120 mg/15 mg film-coated tablets
Sponsors
Instituto De Investigacion Marques De Valdecilla
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| to assess the prevalence of nasal colonization by doxycycline-resistant S. aureus strains | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess differences in the composition of the baseline gut microbiota and at month 12, To assess the development of resistance in the gut microbiota, To assess the prevalence of infections caused by T. pallidum, C. trachomatis, and N. gonorrhoeae, and doxycycline-resistant C. trachomatis. | — |
Outcome results
None listed