TENOFOVIR DISOPROXIL AND EMTRICITABINE
Sponsors
Gilead Sciences Inc., Merck Sharp & Dohme LLC, Instituto De Investigacion Marques De Valdecilla, Rutgers, The State University of New Jersey, University Hospital, Caen
Conditions
Colonization by methicillin-resistant S. aureus and gut microbiota in users of pre-exposure prophylaxis (PrEP) and people living with HIV (PLHIV) with STIs.Covid19HIV InfectionsHIV-1 InfectionHIV-1 preventionHuman Immunodeficiency Virus (HIV-1) infectionPrEP Adherence Monitoring
Phase 2
Effect of Tenofovir/Emtricitabine in Patients Recently Infected With SARS-COV2 (Covid-19) Discharged Home
CompletedNCT04685512
Start: 2020-11-18End: 2021-05-01Updated: 2021-07-01
A Phase 2, Open-label, Multicenter, Randomized Study to Evaluate the Persistence, Safety, and Acceptability of Twice Yearly Long-acting Subcutaneous Lenacapavir for HIV Pre-Exposure Prophylaxis (PrEP) in People Who Would Benefit from PrEP
Active, not recruitingCTIS2023-507891-31-00
Start: 2024-10-11Target: 112Updated: 2025-09-05
Phase 3
Long-Acting HIV Pre-Exposure Prophylaxis Integrated With Sexual and Reproductive Health - cRCT
RecruitingNCT06250504
Start: 2024-02-27End: 2026-10-01Target: 2052Updated: 2026-07-09
A Phase 3, Randomized, Open-Label, Active-Controlled Study to Evaluate a Switch to an Oral Weekly Islatravir/Lenacapavir Regimen in People With HIV-1 Who Are Virologically Suppressed on Standard of Care
Active, not recruitingCTIS2024-514047-28-00
Start: 2025-01-27Target: 98Updated: 2025-09-12
A Phase 3, Randomized, Active-Controlled, Double-Blind Clinical Study to Evaluate the Efficacy and Safety of MK-8527 Oral Once-Monthly as HIV-1 Preexposure Prophylaxis
RecruitingCTIS2025-520610-58-00
Start: 2025-11-19Target: 100Updated: 2025-11-12
Phase 4
IN-US-276-1340: Pre-Exposure Prophylaxis to Prevent HIV Acquisition in US Women: A Demonstration Project
CompletedNCT03058835
Start: 2016-09-01End: 2024-09-01Updated: 2026-08-13
A multicenter, randomized, controlled, open-label, parallel-group clinical trial in men who have sex with men (MSM) and transgender women with risk sexual behaviors for sexually transmitted infections.
Not yet recruitingCTIS2025-525150-19-01
Target: 392Updated: 2026-08-06