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High Dose Dexamethasone in High-Pain-Responders Undergoing Enhanced Recovery Video-Assisted Thoracoscopic Surgery Lobectomy and Segmentectomy – A Randomized Double-Blinded Controlled Trial

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2025-520891-25-00
Enrollment
80
Registered
2025-04-28
Start date
2025-08-28
Completion date
Unknown
Last updated
2025-07-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer

Brief summary

Pain when coughing on the morning on POD1 (Numeric Rating Scale 0-10)

Detailed description

Pain at 5-meter walk test in the morning and afternoon POD1+2 (NRS), Pain when coughing on the afternoon POD1 + morning and afternoon POD2 (NRS), Postoperative length of stay (in days), Cumulative use of rescue analgesics per day during POD1+2, Cumulative use of rescue antiemetics per day during POD1+2, Reasons for re-admission within 30 days (defined as overnight hospital stay after discharge), Intensive Care Unit Days, Pain Catastrophizing Scale (PCS), Morbidity and mortality (30-day), Quality of recovery questionnaire (QoR15) in day 7, Nausea (NRS), Episodes of vomiting

Interventions

Sponsors

Rigshospitalet
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Design outcomes

Primary

MeasureTime frame
Pain when coughing on the morning on POD1 (Numeric Rating Scale 0-10)

Secondary

MeasureTime frame
Pain at 5-meter walk test in the morning and afternoon POD1+2 (NRS), Pain when coughing on the afternoon POD1 + morning and afternoon POD2 (NRS), Postoperative length of stay (in days), Cumulative use of rescue analgesics per day during POD1+2, Cumulative use of rescue antiemetics per day during POD1+2, Reasons for re-admission within 30 days (defined as overnight hospital stay after discharge), Intensive Care Unit Days, Pain Catastrophizing Scale (PCS), Morbidity and mortality (30-day), Quality of recovery questionnaire (QoR15) in day 7, Nausea (NRS), Episodes of vomiting

Countries

Denmark

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026