Whooping cough
Conditions
Brief summary
The magnitude of the antibody responses to pertussis vaccination
Detailed description
Subclass and binding of pertussis-specific antibodies to Fc-receptors, complement and lectin-like receptors post vaccination., Functional antibody profiling post vaccination (including assays covering cytotoxicity, phagocytosis, cytokine production, antigen uptake), Antibody and B cell repertoire post vaccination, The magnitude and quality of Tdap-specific T lymphocytes post vaccination
Interventions
DRUGVaxelis suspension for injection in pre-filled syringe
Diphtheria
DRUGtetanus
DRUGcomponent)
DRUGpoliomyelitis (inactivated)
DRUGand Haemophilus type b conjugate vaccine (adsorbed).
DRUGTriaxis
DRUGsuspension injectable en seringue préremplie.
Vaccin diphtérique
DRUGtétanique et coquelucheux (acellulaire) (adsorbé
DRUGcontenu réduit en antigène(s))
Sponsors
Universite Libre de Bruxelles
Eligibility
Sex/Gender
All
Age
0 Years to 64 Years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The magnitude of the antibody responses to pertussis vaccination | — |
Secondary
| Measure | Time frame |
|---|---|
| Subclass and binding of pertussis-specific antibodies to Fc-receptors, complement and lectin-like receptors post vaccination., Functional antibody profiling post vaccination (including assays covering cytotoxicity, phagocytosis, cytokine production, antigen uptake), Antibody and B cell repertoire post vaccination, The magnitude and quality of Tdap-specific T lymphocytes post vaccination | — |
Countries
Belgium
Outcome results
None listed