pertussis (acellular
Sponsors
GlaxoSmithKline Biologicals, Stichting Radboud University Medical Center, Sanofi Pasteur Inc., Universite Libre de Bruxelles, Immunabs Inc.
Conditions
Generalized Myasthenia Gravis and Ocular Myasthenia GravisInfectionsMeningococcalMeningococcal immunizationPertussis or 'whooping cough'Whooping cough
Phase 1
A Phase II, Randomized, Partially Blinded Study to Assess the Safety, Tolerability and Immunogenicity of Meningococcal Combined ABCWY Vaccine when Administered to Healthy Infants
CompletedCTIS2023-506449-40-00
Start: 2021-11-29End: 2025-11-21Target: 497Updated: 2025-09-01
A Phase 1b/2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Investigate A) the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Ascending Doses of IM-101 in Adult Participants with Generalized Myasthenia Gravis, and B) the Efficacy and Safety of Treatment of IM-101 in Adult Participants with Generalized Myasthenia Gravis and Ocular Myasthenia Gravis
Not yet recruitingCTIS2025-522406-20-00
Target: 51Updated: 2026-02-18
Phase 2
Phase 4
A phase 4, randomised vaccination study in healthy adults to investigate the effects of acellular pertussis vaccine on colonisation with Bordetella pertussis using controlled human infection (KIM-study)
RecruitingCTIS2023-508416-35-00
Start: 2024-10-16Target: 99Updated: 2026-01-26
Maternal determinants of infant immunity to pertussis (MADI-02)
CompletedCTIS2024-517893-73-00
Start: 2023-09-09End: 2025-12-23Target: 240Updated: 2024-10-16