Morphine effects on stress response and social interaction – an exploratory randomized controlled experimental medicine study

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

EU CTIS

Registry ID

CTIS2024-517855-10-00

Acronym

MOR-STRESS-SI

Enrollment

Registered

2024-10-25

Start date

2022-04-20

Completion date

Unknown

Last updated

2024-10-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy volunteers

Brief summary

Subjective distress to exclusion (Visual analog scale)., Neural response to social exclusion (fMRI BOLD-signal).

Detailed description

Morphine effects on behavioral, psychophysiological, and neural responses to personal distance and social approach and avoidance within group., Rejection-induced distress effects on stress-related biomarkers (e.g., cortisol and endocannabinoid levels) and its interaction with morphine.

Interventions

DRUGMorfin Abcur

DRUG10 mg/ml

DRUGinjektionsvätska

DRUGlösning

DRUG0.9% Sodium Chloride Intravenous Infusion Solution

Eligibility

Sex/Gender

All

Age

18 Years to 64 Years

Design outcomes

Primary

Measure	Time frame
Subjective distress to exclusion (Visual analog scale)., Neural response to social exclusion (fMRI BOLD-signal).	—

Secondary

Measure	Time frame
Morphine effects on behavioral, psychophysiological, and neural responses to personal distance and social approach and avoidance within group., Rejection-induced distress effects on stress-related biomarkers (e.g., cortisol and endocannabinoid levels) and its interaction with morphine.	—

Countries

Sweden

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026