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10 mg/ml

DRUG12 trials

Sponsors

Bristol-Myers Squibb International Corporation, Immunogen Inc., Dbv Technologies, Bristol-Myers Squibb Services Unlimited Company, Narodowy Instytut Onkologii Im. Marii Sklodowskiej-Curie-Panstwowy Instytut Badawczy

Conditions

Advanced throat and larynx cancerEarly Stage Non-Small Cell Lung Cancer (NSCLC)HER2 negative breast cancerHealthy volunteersLung CancerMale and female participants ≥ 18 years of age with advanced or metastatic cancersNon-urgent non-cardiac surgical procedure or relative emergency >12h that will require curarisation with rocuronium and decurarisation with sugammadexPeanut allergy

Phase 1

Phase 2

A phase II study of preoperative stereotactic radiation therapy boost combined with short-course immunotherapy (pembrolizumab versus placebo, randomized, double-blind) and standard chemotherapy in patients with newly diagnosed HER2-negative non-metastatic breast cancer with lack of early metabolic response in 18-fluorodeoxyglucoseFDG-PET/CT after 1st chemoterapy cycle
RecruitingCTIS2023-504145-31-00
Narodowy Instytut Onkologii Im. Marii Sklodowskiej-Curie-Panstwowy Instytut BadawczyHER2 negative breast cancer
Start: 2024-06-10Target: 78Updated: 2024-02-21
Morphine effects on stress response and social interaction – an exploratory randomized controlled experimental medicine study
Active, not recruitingCTIS2024-517855-10-00
Linkopings UniversitetHealthy volunteers
Start: 2022-04-20Target: 36Updated: 2024-10-25
The asssessment of the efficacy of induction radiochemotherapy using low doses of ionizing radiation (iCHRTL) in the treatment of patients with advanced throat and larynx cancer
RecruitingCTIS2024-517480-23-00
Narodowy Instytut Onkologii Im. Marii Sklodowskiej-Curie Panstwowy Instytut BadawczyAdvanced throat and larynx cancer
Start: 2022-02-17Target: 40Updated: 2025-01-31
A DOSE-DETERMINATION STUDY OF SUGAMMADEX AS A ROCURONIUM DECURARIZATION AGENT IN CHILDREN UNDER 2 YEARS OF AGE
Not yet recruitingCTIS2025-521946-82-00
Centre Hospitalier Universitaire De Caen NormandieNon-urgent non-cardiac surgical procedure or relative emergency >12h that will require curarisation with rocuronium and decurarisation with sugammadex
Target: 99Updated: 2025-11-12

Phase 3

Randomized, Open-Label, Phase 3 Trial of Nivolumab plus Ipilimumab or Nivolumab plus Platinum-Doublet Chemotherapy versus Platinum-Doublet Chemotherapy in Early Stage NSCLC
CompletedCTIS2022-501360-18-00
Bristol-Myers Squibb International CorporationEarly Stage Non-Small Cell Lung Cancer (NSCLC)
Start: 2017-03-15End: 2024-12-03Target: 194Updated: 2024-12-03
A Phase 3, Double-blind, Placebo-controlled, Randomized Study to Assess the Efficacy and Safety of Epicutaneous Immunotherapy with DBV712 250 μg in 4-7-year-old Children with Peanut Allergy (VITESSE)
Active, not recruitingCTIS2022-502110-85-00
Dbv TechnologiesPeanut allergy
Start: 2024-01-18Target: 126Updated: 2025-12-15
A Phase 3, Randomized, Double-blind Study of Neoadjuvant Chemotherapy plus Nivolumab versus Neoadjuvant Chemotherapy plus Placebo, followed by Surgical Resection and Adjuvant Treatment with Nivolumab or Placebo for Participants with Resectable Stage II-IIIB Non-small Cell Lung Cancer (CheckMate 77T, CHECKpoint pathway and nivoluMAb clinical Trial Evaluation 77T)
Active, not recruitingCTIS2022-502658-15-00
Bristol-Myers Squibb Services Unlimited CompanyResectable Stage II-IIIB Non-small cell lung cancer
Start: 2019-09-22Target: 252Updated: 2025-10-08
2022-501606-35-00 – Randomized, multicenter, open-label, Phase 3 study of mirvetuximab soravtansine in combination with bevacizumab versus bevacizumab alone as maintenance therapy for patients with FRα-high recurrent platinum-sensitive epithelial ovarian, fallopian tube, or primary peritoneal cancers who have not progressed after second-line platinum-based chemotherapy plus bevacizumab (GLORIOSA).
RecruitingCTIS2022-501606-35-01
Immunogen Inc.fallopian tube, or primary peritoneal cancers, Platinum-sensitive epithelial ovarian
Start: 2024-02-21Target: 110Updated: 2026-01-21
A Phase 3, Double-Blind, Placebo-Controlled, Randomized Study to Assess the Safety of Epicutaneous Immunotherapy with DBV712 250 µg in 1-through 3-year-old Children with Peanut Allergy
RecruitingCTIS2025-521697-34-00
Dbv TechnologiesPeanut allergy
Start: 2025-12-01Target: 54Updated: 2026-01-21