Skip to content

The safety of ticagrelor monotherapy after primary percutaneous coronary intervention for ST-elevation myocardial infarction and the effect on intramyocardial haemorrhage

Status
Not yet recruiting
Phases
Phase 4
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-517783-37-00
Enrollment
200
Registered
2024-09-20
Start date
Unknown
Completion date
Unknown
Last updated
2024-09-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ST elevation myocardial infarction (STEMI)

Brief summary

Composite of major adverse cardiac and cerebral events (MACCE), consisting of: Myocardial infarction; Stent thrombosis; Ischemic stroke;Cardiovascular mortality., Infarct size and size of IMH determined by CMR at day 5-8 post-PPCI.

Detailed description

Bleeding complications BARC ≥ 2, All-cause mortality, To compare platelet reactivity between ticagrelor monotherapy and ticagrelor + ASA., To assess the anti-inflammatory effects of ticagrelor with or without aspirin on the inflammation response elicited by the myocardial infarction., To assess coagulation factors after the myocardial infarction in patients using ticagrelor with or without aspirin.

Interventions

Sponsors

Radboud universitair medisch centrum Stichting
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Design outcomes

Primary

MeasureTime frame
Composite of major adverse cardiac and cerebral events (MACCE), consisting of: Myocardial infarction; Stent thrombosis; Ischemic stroke;Cardiovascular mortality., Infarct size and size of IMH determined by CMR at day 5-8 post-PPCI.

Secondary

MeasureTime frame
Bleeding complications BARC ≥ 2, All-cause mortality, To compare platelet reactivity between ticagrelor monotherapy and ticagrelor + ASA., To assess the anti-inflammatory effects of ticagrelor with or without aspirin on the inflammation response elicited by the myocardial infarction., To assess coagulation factors after the myocardial infarction in patients using ticagrelor with or without aspirin.

Countries

Netherlands

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026