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DRUG4 trials

Sponsors

Leiden University Medical Center, Universitair Medisch Centrum Utrecht, University Of Edinburgh, Radboud universitair medisch centrum Stichting

Conditions

(Chronic) Peripheral (occlusive) arterial disease (PAD)Intracerebral haemorrhageST elevation myocardial infarction (STEMI)prosthetic joint infection

Phase 3

CLEAR-PATH A randomized placebo-controlled double-blind trial studying the effect of single antiplatelet therapy (clopidogrel) versus dual antiplatelet therapy (clopidogrel/acetylsalicylic acid) on the occurrence of atherothrombotic events following lower extremity peripheral transluminal angioplasty

Not yet recruitingCTIS2024-513363-15-01

Universitair Medisch Centrum Utrecht(Chronic) Peripheral (occlusive) arterial disease (PAD)

Target: 1696Updated: 2025-08-14

Phase 4

Rifampicin Combination Therapy versus Targeted Antimicrobial Monotherapy in the Oral Antimicrobial Treatment Phase of Staphylococcal Prosthetic Joint Infection

RecruitingCTIS2022-501620-26-00

Leiden University Medical Centerprosthetic joint infection

Start: 2023-05-15Target: 316Updated: 2025-07-07

The safety of ticagrelor monotherapy after primary percutaneous coronary intervention for ST-elevation myocardial infarction and the effect on intramyocardial haemorrhage

Not yet recruitingCTIS2024-517783-37-00

Radboud universitair medisch centrum StichtingST elevation myocardial infarction (STEMI)

Target: 200Updated: 2024-09-20

Antiplatelet Secondary Prevention International Randomised study after INtracerebral haemorrhaGe - SM

RecruitingCTIS2024-516188-10-00

University Of EdinburghIntracerebral haemorrhage

Start: 2025-10-07Target: 596Updated: 2025-11-17

Related Papers

RIFAMPICIN COMBINATION THERAPY VERSUS TARGETED ANTIMICROBIAL MONOTHERAPY IN THE ORAL ANTIMICROBIAL TREATMENT PHASE OF STAPHYLOCOCCAL PROSTHETIC JOINT INFECTION (RICOTTA-TRIAL): PROTOCOL FOR A RANDOMIZED, CONTROLLED, OPEN-LABEL, NON-INFERIORITY TRIAL

Orthopaedic Proceedings2024-11-221 citations