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CRYSTAL : Comparison of topical hydrocortisone versus dexamethasone treatment for inflammatory secretions of the conjunctiva in patients with ocular prostheses

Status
Not yet recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-517441-14-00
Acronym
35RC21_8901
Enrollment
30
Registered
2024-10-30
Start date
Unknown
Completion date
Unknown
Last updated
2025-06-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

inflammatory secretions of the conjunctiva (Eye desease)

Brief summary

Secretion Self-Rating Scale score. This 40-point score is calculated as the sum of 4 criteria, each scored on 10 points. (Jacobs et al.; Maucourant et al.)

Detailed description

1) Bulbar conjunctival inflammation score and tarsal conjunctival inflammation score according to the grades of Saini et al., 2) Secretion frequency (score out of 10) according to the secretion analysis scale (Jacobs et al.) - Colour of secretions (score out of 10) according to the secretion analysis scale (Jacobs et al.) - Amount of secretions (score out of 10) according to the secretion analysis scale (Jacobs et al.) - Thickness/Viscosity of secretions (score out of 10) according to the secretion analysis scale (Jacobs et al.), 3) OSDI quality of life score adapted to prosthesis wearers, scored on 40 points (10 items with a maximum of 4 points per item) (Maucourant et al.)

Interventions

Sponsors

Centre Hospitalier Universitaire De Rennes
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Design outcomes

Primary

MeasureTime frame
Secretion Self-Rating Scale score. This 40-point score is calculated as the sum of 4 criteria, each scored on 10 points. (Jacobs et al.; Maucourant et al.)

Secondary

MeasureTime frame
1) Bulbar conjunctival inflammation score and tarsal conjunctival inflammation score according to the grades of Saini et al., 2) Secretion frequency (score out of 10) according to the secretion analysis scale (Jacobs et al.) - Colour of secretions (score out of 10) according to the secretion analysis scale (Jacobs et al.) - Amount of secretions (score out of 10) according to the secretion analysis scale (Jacobs et al.) - Thickness/Viscosity of secretions (score out of 10) according to the secretion analysis scale (Jacobs et al.), 3) OSDI quality of life score adapted to prosthesis wearers, scored on 40 points (10 items with a maximum of 4 points per item) (Maucourant et al.)

Countries

France

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026