collyre en solution en récipient unidose
Sponsors
Vaestra Goetalandsregionen, Hopital Fondation Adolphe De Rothschild, eyeDNA Therapeutics, Centre Hospitalier Universitaire De Rennes, University Of Cologne
Conditions
Corneal Neovascularization in Aniridia-associated KeratopathyPathologically prevascularized corneas due to herpetic keratopathy prior to “high-risk” corneal transplantation (keratoplasty)Patient with severe eye chemical burnsRetinopathy of Prematurityinflammatory secretions of the conjunctiva (Eye desease)retinitis pigmentosa
Phase 1
Phase 2
SYMBOL CLINICAL : Treatment of severe ocular chemical burns by subconjunctival injection of allogeneic mesenchymal stem cells:
a multicentre, single-arm, open-label phase II trial
Not yet recruitingCTIS2023-509713-37-00
Target: 21Updated: 2025-12-09
Antisense Oligonucleotide Eye Drops Against IRS-1 to Treat Pathological Corneal Neovascularisation in Aniridia-Associated Keratopathy (Olisens-Aniridia)
Not yet recruitingCTIS2025-522609-39-00
Target: 20Updated: 2026-01-23
Antisense Oligonucleotide Eye Drops against IRS-1 to Optimize Pretransplant Lymphangio-regression Prior to High-Risk Keratoplasty (Olisens-Precon)
Not yet recruitingCTIS2025-522099-10-00
Target: 10Updated: 2026-01-28
Phase 3
A Randomized Intervention, Multi-Center Study to Determine the Role of Dexamethasone eye drops against proliferative retinopathy of prematurity
Active, not recruitingCTIS2023-505318-97-00
Start: 2022-09-22Target: 100Updated: 2025-12-11
CRYSTAL : Comparison of topical hydrocortisone versus dexamethasone treatment for inflammatory secretions of the conjunctiva in patients with ocular prostheses
Not yet recruitingCTIS2024-517441-14-00
Target: 30Updated: 2025-06-05