Excision-autograft surgery in burn patient
Conditions
Brief summary
Post-operative infection defined as Post-operative sepsis and/or surgical site infection, and/or autograft lysis requiring a new autograft within 7 days after surgery
Detailed description
- 90 days mortality, - Skin raft lysis requiring a new autograft procedure, - Post-operative pulmonary infection, - Number of days of hospitalization until complete healing (> 95% total burn surface area), - Number of hospitalization days living without antibiotic therapy at D28 and D90, - Multiresistant bacteria (15) colonization of infection at D28 and D90
Interventions
DRUGPlacebo de Cefazoline / Piperaciline / Tazobactam
DRUGCEFAZOLIN
DRUGPIPERACILLINE TAZOBACTAM VIATRIS 4 g/0
DRUG5 g
Sponsors
Assistance Publique Hopitaux De Paris
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Post-operative infection defined as Post-operative sepsis and/or surgical site infection, and/or autograft lysis requiring a new autograft within 7 days after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| - 90 days mortality, - Skin raft lysis requiring a new autograft procedure, - Post-operative pulmonary infection, - Number of days of hospitalization until complete healing (> 95% total burn surface area), - Number of hospitalization days living without antibiotic therapy at D28 and D90, - Multiresistant bacteria (15) colonization of infection at D28 and D90 | — |
Countries
France
Outcome results
None listed