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poudre pour solution pour perfusion

DRUG15 trials

Sponsors

Hospices Civils De Lyon, Centre Hospitalier Regional Universitaire De Tours, Assistance Publique Hopitaux De Paris, Assistance Publique Hopitaux De Marseille, Institut Paoli-Calmettes

Conditions

Acute myeloid leukemia (AML)Advanced Epithelial Ovarian Cancer (including Fallopian Tube or Primary Peritoneal cancers)Advanced Metastatic Ocular/Uveal MelanomaAdvanced pulmonary or gastroenteropancreatic poorly differentiated neuroendocrine carcinomas (NECs)Breast CancerEndometrial cancerExcision-autograft surgery in burn patientHepato carcinoma cancer

Phase 2

CASPER-ATG-IPC 2023-015 : Reinforced prophylaxis of GVH in elderly patients with haematological malignancies receiving haploidentical allogeneic hematopoietic stem cell transplantation: use of a low dose of post-allograft anti-lymphocytic serum.
RecruitingCTIS2023-506648-18-00
Institut Paoli-Calmetteshaematological malignancies
Start: 2025-01-14Target: 27Updated: 2025-12-04
REFRaME-O1: A Phase 2/3 Open-label Study Evaluating the Efficacy and Safety of Luveltamab Tazevibulin (STRO-002) versus Investigator’s Choice (IC) Chemotherapy in Women with Relapsed Platinum-resistant Epithelial Ovarian Cancer (Including Fallopian Tube or Primary Peritoneal Cancers) Expressing Folate Receptor Alpha (FOLR1)
CompletedCTIS2024-512477-27-00
Sutro Biopharma Inc.Advanced Epithelial Ovarian Cancer (including Fallopian Tube or Primary Peritoneal cancers)
End: 2025-03-28Target: 193Updated: 2025-04-18
Hepatocellular Carcinoma on Cirrhosis With Child A/B7 and Hepatic Intra Arterial Injection of Idarubicin/Lipiodol Emulsion : Phase II, single arm, Multicentric
Not yet recruitingCTIS2024-515456-20-00
Centre Hospitalier Universitaire De MontpellierHepato carcinoma cancer
Target: 53Updated: 2025-03-21
AAA-IPC 2011-003 - Prospective and multicentre evaluation of 3 different doses of IV busulfan associated with fludarabine and thymoglobuline in the conditioning of allogeneic stem cell transplantation (SCT) from a matched related or unrelated donor in patients with poor prognosis myeloïd malignancies
Not yet recruitingCTIS2024-516435-27-00
Institut Paoli CalmettesHigh-risk myeloïd malignancies
Target: 177Updated: 2024-11-05
A Phase II, Multi-centre, Open label, Randomised Study to Evaluate the Anti-tumour Activity of Roginolisib (IOA-244) in Patients with Advanced/Metastatic Ocular/Uveal Melanoma
RecruitingCTIS2024-514333-37-00
iOnctura SAAdvanced Metastatic Ocular/Uveal Melanoma
Start: 2025-02-25Target: 43Updated: 2025-10-23
Master Protocol: A Phase 1b / 2, Multicenter, Multi Arm Study of Evorpacept in Combination with Anti-cancer Therapies in Advanced / Metastatic Malignancies (ASPEN-09) Substudy Protocol: A Single-arm Phase 2 Multicenter Study of Evorpacept in Combination with Trastuzumab and Chemotherapy in Participants with Metastatic HER2-Positive Breast Cancer (ASPEN-09-03)
Not yet recruitingCTIS2025-522012-16-00
Alx Oncology Holdings Inc.Breast Cancer
Target: 36Updated: 2026-01-23
A Phase 2 Study of ACR-368 Therapy in Subjects with Endometrial Cancer
Not yet recruitingCTIS2025-524542-10-00
Acrivon Therapeutics Inc.Endometrial cancer
Target: 36Updated: 2026-03-24

Phase 3

INduction in Sensitized kidney Transplant recipients without pre-Existing donor-specific AntiboDies: a randomized multicentre trial between a lymphocyte depleting and basiliximab (INSTEAD)
RecruitingCTIS2022-502007-30-00
Centre Hospitalier Regional Universitaire De ToursKidney transplant
Start: 2023-11-07Target: 244Updated: 2023-06-30
Linezolid or vancomycin surgical site infection prophylaxis LOVip
RecruitingCTIS2023-504986-22-00
Assistance Publique Hopitaux De Marseillesurgical antibiotic prophylaxis
Start: 2024-09-30Target: 1160Updated: 2025-12-12
Phase III study comparing GVHD prophylaxis with ATG-thymoglobulin to ATLG-grafalon in elderly patients with acute myeloid leukemia or myelodysplastic syndrome and receiving an allogeneic hematopoietic stem cell transplantation with a 10/10 HLA matched unrelated donor following a reduced intensity conditioning regimen by fludarabine-treosulfan (OPTISAGE)
RecruitingCTIS2023-504555-27-00
Assistance Publique Hopitaux De ParisAcute myeloid leukemia (AML), Myelodysplastic syndrome (MDS)
Start: 2023-11-28Target: 324Updated: 2025-07-11
Interest of peri operative CHemotherapy In patients with CINSARC high-risk localized Soft Tissue Sarcoma
RecruitingCTIS2024-515384-62-00
Oncopole Claudius RegaudSoft Tissue Sarcoma
Start: 2020-10-09Target: 600Updated: 2025-12-23
A2B-trial Antibioprophylaxis for excision-graft surgery in burn patient : a multicenter randomized double-bling study
RecruitingCTIS2024-514349-13-00
Assistance Publique Hopitaux De ParisExcision-autograft surgery in burn patient
Start: 2020-10-11Target: 506Updated: 2025-10-10
LANdiolol MIcrocirculatory effects during Septic chOc (MILANOS)
RecruitingCTIS2024-512757-24-00
Assistance Publique Hopitaux De ParisPatients with microcirculatory abnormalities during septic shock
Start: 2022-07-18Target: 44Updated: 2025-07-18
GCO-003 TARLANEC A randomized phase III trial study comparing tarlatamab with standard of care chemotherapy in patients with pre-treated advanced, refractory pulmonary or gastroenteropancreatic poorly differentiated neuroendocrine carcinomas
Not yet recruitingCTIS2024-515948-23-00
Intergroupe Francophone De Cancerologie ThoraciqueAdvanced pulmonary or gastroenteropancreatic poorly differentiated neuroendocrine carcinomas (NECs)
Target: 129Updated: 2025-09-02

Phase 4