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Avelumab Short Maintenance Trial

Status
Not yet recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-512975-11-01
Acronym
NL75848.056.20
Enrollment
121
Registered
2025-01-28
Start date
Unknown
Completion date
Unknown
Last updated
2025-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

urothelial cancer, Bladder cancer, muscle invasive bladder cancer

Brief summary

18months overallsurvival (OS)

Detailed description

OS in PD-L1 positive and PD-L1 negative tumors, in patients with visceral versus non-visceral metastases, in patients with CR/PR as best response to chemotherapy versus SD, and in retreated patients. PFS in PD-L1 positive and PD-L1 negative tumors, and in retreated patients. ORR per RECIST 1.1 in retreated patients. Duration ofresponse. Disease control (defined as complete response, partial response, non—complete response or non-progressive disease, orstable disease at 24 weeks after initi

Interventions

Sponsors

Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Design outcomes

Primary

MeasureTime frame
18months overallsurvival (OS)

Secondary

MeasureTime frame
OS in PD-L1 positive and PD-L1 negative tumors, in patients with visceral versus non-visceral metastases, in patients with CR/PR as best response to chemotherapy versus SD, and in retreated patients. PFS in PD-L1 positive and PD-L1 negative tumors, and in retreated patients. ORR per RECIST 1.1 in retreated patients. Duration ofresponse. Disease control (defined as complete response, partial response, non—complete response or non-progressive disease, orstable disease at 24 weeks after initi

Countries

Netherlands

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026