Bavencio 20 mg/mL concentrate for solution for infusion
Sponsors
Gilead Sciences Inc., Rigshospitalet, Groupe Oncologie Radiotherapie Tete Cou, Merck Healthcare KGaA, Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
Conditions
Bladder cancerBreast CancerCancerCentral Nervous System TumorsGastrointestinal Stromal Tumors (GIST)Locally Advanced/Metastatic Urothelial CancerPhase Ib and Phase II part 1: HPV-16 positive recurrent or metastatic malignancies including oropharyngeal squamous cell carcinoma of head and neckRecurrent Metastatic Head and Neck Cancer
Phase 1
Single-arm, multicenter Phase I/Ib study of avelumab + lenvatinib in children with primary CNS tumors
SuspendedCTIS2024-512940-51-00
Start: 2021-11-24Target: 23Updated: 2025-10-16
A phase Ib/II trial evaluating the combination of TG4001 and avelumab in patients with HPV-16 positive recurrent or metastatic malignancies
Active, not recruitingCTIS2024-515119-23-00
Start: 2017-08-29Target: 142Updated: 2025-12-02
AcSé-ESMART: European Proof-of-Concept Therapeutic Stratification Trial of Molecular Anomalies in Relapsed or Refractory Tumors
RecruitingCTIS2024-514791-40-00
Start: 2016-08-03Target: 398Updated: 2025-10-06
Phase 2
A Phase II Open-Label Study of Sacituzumab Govitecan in Unresectable Locally Advanced/Metastatic Urothelial Cancer
RecruitingCTIS2023-508302-24-00
Start: 2019-05-07Target: 116Updated: 2025-10-22
ProTarget - A Danish Nationwide Clinical Trial on Targeted Anti‐Cancer Treatment based on Genomic Profiling
RecruitingCTIS2023-510527-29-00
Start: 2020-09-01Target: 600Updated: 2025-04-25
Neoadjuvant AXITINIB plus AVELUMAB for patients with localized RCC and a moderate to high risk of recurrence (N17JAV)
Not yet recruitingCTIS2024-515825-27-00
Target: 40Updated: 2024-07-11
CHemotherapy And Sequential ImmunoTherapy for locally advanced urothelial cancer: the CHASIT study
Not yet recruitingCTIS2024-516940-24-00
Target: 58Updated: 2025-11-05
A phase II study evaluating the efficacy and the safety of TPEx followed by a maintenance with the combination of avelumab and cetuximab in First Line Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (R/M SCCHN).
SuspendedCTIS2023-510559-41-00
Start: 2025-01-02Target: 70Updated: 2025-05-23
DISCUS: A Randomised Phase II Study Comparing 3 vs 6 Cycles of Platinum-based Chemotherapy Prior to Maintenance Avelumab in Advanced Urothelial Cancer
RecruitingCTIS2024-518244-20-01
Start: 2022-04-25Target: 193Updated: 2025-11-20
A Phase II, single arm Study of avelumab in combination with Axitinib in Patients with unresectable/metastatic Gastrointestinal Stromal Tumor after failure of standard therapy - AXAGIST
Active, not recruitingCTIS2024-519176-95-00
Start: 2019-05-08Target: 58Updated: 2025-01-13
DEPECA-1 – DEfeating PEnile CAncer 1 – A Phase II study to evaluate a first-line systemic therapy with enfortumab vedotin plus avelumab for advanced and metastatic penile carcinoma
RecruitingCTIS2025-521644-37-00
Start: 2025-11-28Target: 25Updated: 2025-10-29
A Phase II Randomized Clinical Trial Comparing Two Cycles Versus Four Cycles of Combination Therapy with Cetuximab, Avelumab, Cisplatin, and Docetaxel in Patients with Recurrent Metastatic Head and Neck Cancer - AVETUX-HN
RecruitingCTIS2025-521738-27-00
Start: 2025-12-15Target: 126Updated: 2025-11-17
Phase 3
A Phase III randomized trial of avelumab-cetuximab- Radiotherapy versus standards of care in locally advanced squamous cell carcinoma of the head and neck (REACH)
Active, not recruitingCTIS2024-513964-24-00
Start: 2017-09-14Target: 706Updated: 2026-01-16
An Open-Label, Multicenter Follow-up Study to Collect Long-term Data on Participants from Multiple Avelumab (MSB0010718C) Clinical Studies
Active, not recruitingCTIS2024-514274-46-00
Start: 2019-06-21Target: 13Updated: 2025-12-19
A–BRAVE-Trial. ADJUVANT TREATMENT FOR HIGH-RISK TRIPLE NEGATIVE BREAST CANCER
PATIENTS WITH THE ANTI-PD-L1 ANTIBODY AVELUMAB: A PHASE III
RANDOMIZED TRIAL
CompletedCTIS2024-514515-10-00
Start: 2016-06-16End: 2025-10-09Target: 450Updated: 2025-10-14
Avelumab Short Maintenance Trial
Not yet recruitingCTIS2024-512975-11-01
Target: 121Updated: 2025-01-28