Focal cerebral arteriopathy and childhood stroke Focal cerebral arteriopathy (FCA) is an inflammatory vessel wall disease provoked by infection.
Conditions
Brief summary
The primary outcome is change in FCA Severity Score (FCASS) from baseline to 1 month
Detailed description
Neurological deficits over time as determined by PSOM, RRQ, modified Rankin scale (mRS) and Vineland Adaptive Behaviour Scale (VABS) at 6 and 12 months, Neurocognitive outcome at 12 months, Recurrence-free survival, Change in FCASS at (3) and 6 months, Residual vasculopathy at 6 months
Interventions
DRUGMethylprednisolut 16 mg
DRUGPrednisolon 50 mg JENAPHARM
DRUGpoudre pour solution injectable
DRUGAprednislon 25 mg Tabletten
DRUGSolu-Medrol® 500 mg – Trockenstechampulle mit Lösungsmittel
DRUGSOLUPRED 5 mg
DRUGcomprimé effervescent
DRUGMETHYLPREDNISOLONE
DRUGAprednislon 5 mg Tabletten
DRUGSolu-Medrol® 1000 mg – Trockenstechampulle mit Lösungsmittel
DRUGPREDNISOLONE
DRUGMethylprednisolut 1000 mg
DRUGMethylprednisolut 32 mg
DRUGMethylprednisolut 250 mg
Sponsors
Insel Gruppe AG
Eligibility
Sex/Gender
All
Age
0 Years to 17 Years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome is change in FCA Severity Score (FCASS) from baseline to 1 month | — |
Secondary
| Measure | Time frame |
|---|---|
| Neurological deficits over time as determined by PSOM, RRQ, modified Rankin scale (mRS) and Vineland Adaptive Behaviour Scale (VABS) at 6 and 12 months, Neurocognitive outcome at 12 months, Recurrence-free survival, Change in FCASS at (3) and 6 months, Residual vasculopathy at 6 months | — |
Countries
Austria, Denmark, France, Germany, Sweden
Outcome results
None listed