Prednisolon 5 mg JENAPHARM

DRUG5 trials

Sponsors

Insel Gruppe AG, AbbVie Deutschland GmbH & Co. KG, Klinikum der Universitaet Muenchen AöR, Goethe University Frankfurt, Sparrow Pharmaceuticals Inc.

Conditions

Focal cerebral arteriopathy and childhood stroke Focal cerebral arteriopathy (FCA) is an inflammatory vessel wall disease provoked by infection.Giant Cell ArteritisInflammatory cardiovascular involvement due to COVID-19Patients with biopsy-proven virus-negative inflammatory dilated or nondilated left ventricular cardiomyopathy and persistent deterioration of cardiac function despite optimal medical treatment (OMT) for heart failurePolymyalgia rheumatica (PMR)defined by Cardiovascular magnetic resonance imaging

Phase 2

A multicenter, randomized, double-blind, placebo-controlled TRial evaluating Immunosuppressive treatment in patients with chronic virus-Negative Inflammatory cardiomyopaThY (TRINITY trial)

CompletedCTIS2024-512451-20-00

Klinikum der Universitaet Muenchen AöRPatients with biopsy-proven virus-negative inflammatory dilated or nondilated left ventricular cardiomyopathy and persistent deterioration of cardiac function despite optimal medical treatment (OMT) for heart failure

Start: 2023-02-28End: 2025-04-14Target: 130Updated: 2024-10-14

A trial of prednisolone in combination with SPI-62 or placebo in participants with polymyalgia rheumatica (PMR)

CompletedCTIS2024-517406-29-00

Sparrow Pharmaceuticals Inc.Polymyalgia rheumatica (PMR)

Start: 2022-07-26End: 2025-04-25Target: 72Updated: 2025-02-14

Phase 3

High Dose Steroids in Children with Stroke and Unilateral Focal Arteriopathy: A Multicentre Randomized Controlled Trial

Not yet recruitingCTIS2022-500631-36-00

Insel Gruppe AGFocal cerebral arteriopathy and childhood stroke Focal cerebral arteriopathy (FCA) is an inflammatory vessel wall disease provoked by infection.

Target: 45Updated: 2025-11-14

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Upadacitinib in Subjects with Giant Cell Arteritis

CompletedCTIS2023-505476-29-00

AbbVie Deutschland GmbH & Co. KGGiant Cell Arteritis

Start: 2019-04-05End: 2025-02-24Target: 201Updated: 2024-10-28

Randomised placebo controlled clinical trial of efficacy of MYOcardial protection in postacute inFLAMmatory cardiac involvEment due to COVID-19 (MYOFLAME-19)

Active, not recruitingCTIS2024-516463-84-00

Goethe University Frankfurtdefined by Cardiovascular magnetic resonance imaging, Inflammatory cardiovascular involvement due to COVID-19

Start: 2022-12-13Target: 280Updated: 2025-04-25