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zolpidem tartrate

DRUG8 trials

Sponsors

Massachusetts General Hospital, Sanofi, Stanford University, Eisai Inc., Johns Hopkins University

Conditions

Breast CancerHeart FailureHot FlashesInsomniaInsomnia ChronicSleep DisordersSleep DisturbanceSleep Initiation and Maintenance Disorders

Phase 2

Xyrem(Sodium Oxybate) and Ambien(Zolpidem Tartrate) in the Treatment of Chronic Insomnia.
CompletedNCT00383643
Stanford UniversitySleep Initiation and Maintenance Disorders
Start: 2006-05-31End: 2009-12-31Updated: 2017-06-01

Phase 3

Study of the Efficacy and Safety of Lemborexant in Subjects 55 Years and Older With Insomnia Disorder (SUNRISE 1)
CompletedNCT02783729
Eisai Inc.Insomnia
Start: 2016-05-31End: 2018-01-30Updated: 2024-11-12

Phase 4

Residual Effects of Zolpidem Tartrate Extended Release and Eszopiclone Vs Placebo
CompletedNCT00283790
SanofiInsomnia
Start: 2006-01-31End: 2006-04-30Target: 36Updated: 2008-04-03
Ambien CR For Treatment Of Insomnia Associated With Depression When Used Concomitantly With Lexapro
CompletedNCT00296179
SanofiInsomnia
Start: 2006-02-28Target: 372Updated: 2008-07-28
Ambien CR vs. Placebo For Treatment Of Insomnia Associated With Anxiety When Used Concomitantly With Escitalopram (Lexapro)
CompletedNCT00296790
SanofiInsomnia
Start: 2006-02-28End: 2007-02-28Target: 372Updated: 2007-10-12
Improving Sleep Quality in Heart Failure
CompletedNCT03307005
Johns Hopkins UniversityHeart Failure, Sleep Disturbance
Start: 2017-11-01End: 2019-01-25Updated: 2020-02-11
Partial Reinforcement II: Three Approaches to Maintenance Therapy for Chronic Insomnia
CompletedNCT03774810
University of PennsylvaniaInsomnia, Insomnia Chronic
Start: 2019-04-15End: 2024-09-30Updated: 2025-05-09

Unknown Phase

Venlafaxine With or Without Zolpidem in Treating Hot Flashes and Associated Sleep Disorders in Women With Breast Cancer OR at High Risk for Developing Breast Cancer
CompletedNCT00084669
Massachusetts General HospitalBreast Cancer, Hot Flashes, Sleep Disorders
Start: 2004-05-31End: 2010-03-31Target: 119Updated: 2010-04-28

Related Papers

P.030 Impact of lemborexant on daytime sleepiness/alertness in participants with comorbid insomnia and mild obstructive sleep apnea
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques2025-06-01
P.031 Consistency of objective sleep maintenance data in Chinese and North American/European subjects with insomnia in lemborexant phase 3 studies
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques2025-06-01
0550 Lemborexant’s Effects on Rapid Eye Movement (REM) Sleep Architecture in Asian and Non-Asian Adults with Insomnia: Comparative Analysis from 3 Studies
SLEEP2025-05-01
Effect of lemborexant on sleep architecture in participants with insomnia disorder and mild obstructive sleep apnea
Sleep Medicine2024-12-177 citations
O030 Impact of lemborexant on daytime sleepiness/alertness in participants with comorbid insomnia and mild obstructive sleep apnea
SLEEP Advances2024-10-01
Respiratory safety of lemborexant in adult and elderly subjects with moderate‐to‐severe chronic obstructive pulmonary disease
Journal of Sleep Research2024-09-123 citations
Efficacy and safety of insomnia treatment with lemborexant in older adults: analyses from three clinical trials
Drugs & Aging2024-08-0910 citations
Lemborexant and Daridorexant for the Treatment of Insomnia
The Journal of Clinical Psychiatry2023-09-285 citations
P.054 Older subjects with insomnia disorder and comorbid pain at baseline: response to Lemborexant
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques2023-06-01
P.047 Effect of lemborexant on sleep architecture in subjects with comorbid insomnia and mild obstructive sleep apnea from a phase 3 trial
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques2023-06-01
P.053 Efficacy of lemborexant in adults with insomnia is supported by improvements in both objective and subjective measures
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques2023-06-01
0354 Effect of Lemborexant on Sleep Architecture in Subjects with Comorbid Insomnia and Mild Obstructive Sleep Apnea from a Ph 3 Trial
SLEEP2023-05-012 citations
0351 Differential Effect of Lemborexant and Zolpidem on Wake Across the Night in Patients with Insomnia Disorder
SLEEP2023-05-01
0407 Impact of Lemborexant on Daytime Ratings of Sleepiness/Alertness in Subjects with Insomnia Disorder and Baseline Sleepiness
SLEEP2023-05-01
0224 Chronic change in sleep oscillation expression in older adults with insomnia with zolpidem or lemborexant and its effect on memory
SLEEP2023-05-01
Effect of Lemborexant Treatment on Polysomnographic Sleep Measures in Older Adults with Insomnia and Objective Short Sleep Duration (P4-13.003)
Neurology2023-04-25
Effect of Lemborexant on Early Morning Awakening in Elderly Subjects with Severe Problems with Waking Too Early (S6.010)
Neurology2023-04-25
Comparison of the treatment effectiveness between lemborexant and zolpidem tartrate extended-release for insomnia disorder subtypes defined based on polysomnographic findings.
2023-03-0110 citations
0451 Effect of Lemborexant Treatment on Polysomnographic Sleep Measures in Older Adults with Insomnia and Objective Short Sleep
SLEEP2022-05-25
0453 Lemborexant Exposure Is Independent of Race
SLEEP2022-05-25

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