UC-MSCs

BIOLOGICAL18 trials

Sponsors

Affiliated Hospital to Academy of Military Medical Sciences, The First Affiliated Hospital of Dalian Medical University, Xijing Hospital, ZhiYong Peng, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Conditions

2019 Novel Coronavirus PneumoniaAcute Respiratory Distress SyndromeCOVID-19Cerebral PalsyCirrhosis Due to Hepatitis BCorona Virus Disease 2019(COVID-19)Covid19Decompensated Cirrhosis

Phase 1

Safety and Efficacy of UC-MSCs in Patients With Psoriasis Vulgaris

Affiliated Hospital to Academy of Military Medical SciencesPsoriasis Vulgaris

Start: 2015-04-30End: 2016-12-31Target: 30Updated: 2015-07-08

Clinical Research of Human Mesenchymal Stem Cells in the Treatment of COVID-19 Pneumonia

Puren Hospital Affiliated to Wuhan University of Science and TechnologyCOVID-19

Start: 2020-02-01End: 2020-06-30Target: 30Updated: 2020-04-09

Stem Cells and Secretomes for Infertility Therapy in Polycystic Ovary Syndrome (PCOS) Patients With Insulin Resistance.

CompletedNCT05279768

PT. Prodia Stem Cell IndonesiaPolycystic Ovary Syndrome

Start: 2022-09-01End: 2025-01-20Updated: 2026-02-25

Study of Human Umbilical Cord Mesenchymal Stem Cell in Patients With Cirrhosis Due to Hepatitis B (Compensation Stage)

Renmin Hospital of Wuhan UniversityCirrhosis Due to Hepatitis B

Start: 2021-07-20End: 2023-08-20Target: 20Updated: 2022-08-19

Phase I Clinical Trial of UC-MSCs in the Treatment of Knee Osteoarthritis

RecruitingNCT06463847

Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyKnee Osteoarthritis

Start: 2024-06-30End: 2026-10-30Target: 18Updated: 2024-07-01

Human Umbilical Cord Mesenchymal Stem Cell Injection for Diabetic Nephropathy

RecruitingNCT07822152

Tongji HospitalDiabetic Nephropathy

Start: 2026-03-25End: 2028-03-25Target: 15Updated: 2026-09-16

Phase 2

Umbilical Cord(UC)-Derived Mesenchymal Stem Cells(MSCs) Treatment for the 2019-novel Coronavirus(nCOV) Pneumonia

ZhiYong PengPneumonia, Ventilator-Associated, Pneumonia, Viral

Start: 2020-02-06End: 2020-12-30Target: 16Updated: 2020-07-01

Treatment With Human Umbilical Cord-derived Mesenchymal Stem Cells for Severe Corona Virus Disease 2019 (COVID-19)

CompletedNCT04288102

Beijing 302 HospitalCorona Virus Disease 2019(COVID-19)

Start: 2020-03-05End: 2020-07-09Updated: 2020-08-19

Cellular Immuno-Therapy for COVID-19 ARDS Randomized Clinical Trial

CompletedNCT04865107

Ottawa Hospital Research InstituteAcute Respiratory Distress Syndrome, Covid19

Start: 2021-04-27End: 2022-04-01Updated: 2025-07-31

Treatment With Human Umbilical Cord-derived Mesenchymal Stem Cells for Decompensated Cirrhosis

Beijing 302 HospitalDecompensated Cirrhosis

Start: 2021-09-01End: 2023-12-31Target: 240Updated: 2021-11-16

Human Umbilical Cord-derived Mesenchymal Stem Cells for Decompensated Cirrhosis (MSC-DLC-2)

RecruitingNCT05224960

Beijing 302 HospitalDecompensated Cirrhosis

Start: 2024-06-27End: 2027-06-20Target: 140Updated: 2024-10-18

Efficacy and Safety of Umbilical Cord Mesenchymal Stem Cells in the Treatment of Long COVID-19

WithdrawnNCT05719012

Shanghai East HospitalLong COVID-19

Start: 2023-04-01End: 2024-03-30Updated: 2023-11-21

Phase II Clinical Trial of UC-MSCs in the Treatment of Knee Osteoarthritis

RecruitingNCT07547735

Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyKnee Osteoarthritis

Start: 2025-03-20End: 2028-05-30Target: 100Updated: 2026-04-23

Unknown Phase

Transplantation of Umbilical Cord-derived Mesenchymal Stem Cells Via Different Routes

The First Affiliated Hospital of Dalian Medical UniversityCerebral Palsy

Start: 2018-04-30End: 2020-12-31Target: 44Updated: 2018-01-30

The Safety and Effects of Mesenchymal Stem Cell (MSCs) in the Treatment of Rheumatoid Arthritis

Xijing HospitalRheumatoid Arthritis

Start: 2017-12-26End: 2020-06-30Target: 250Updated: 2019-01-09

Study of Human Umbilical Cord Mesenchymal Stem Cells in the Treatment of Severe COVID-19

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology2019 Novel Coronavirus Pneumonia, COVID-19

Start: 2020-04-20End: 2022-02-15Target: 48Updated: 2020-04-14

Therapy for Pneumonia Patients iInfected by 2019 Novel Coronavirus

WithdrawnNCT04293692

Puren Hospital Affiliated to Wuhan University of Science and TechnologyCOVID-19

Start: 2020-02-24End: 2020-02-25Updated: 2020-03-18

Clinical Research of UC-MSCs in the Treatment of Diabetic Nephropathy

Renmin Hospital of Wuhan UniversityDiabetic Nephropathy

Start: 2020-09-25End: 2021-12-31Target: 38Updated: 2020-09-24

Related Papers

Long-term outcomes of mesenchymal stem cell therapy in severe COVID-19 patients: 3-year follow-up of a randomized, double-blind, placebo-controlled trial

Stem Cell Research & Therapy2025-02-254 citations

Human mesenchymal stem cell therapy in severe COVID-19 patients: 2-year follow-up results of a randomized, double-blind, placebo-controlled trial.

2023-05-0520 citations

Human mesenchymal stem cells treatment for severe COVID-19: 1-year follow-up results of a randomized, double-blind, placebo-controlled trial.

2021-12-2581 citations

Effect of human umbilical cord-derived mesenchymal stem cells on lung damage in severe COVID-19 patients: a randomized, double-blind, placebo-controlled phase 2 trial.

2021-02-10188 citations