treprostinil diethanolamine

DRUG9 trials

Sponsors

United Therapeutics

Conditions

Hypertension, PulmonaryPulmonary Arterial HypertensionSclerodermaSystemic Sclerosis

Phase 1

Pharmacokinetics of Oral Treprostinil in Patients With Systemic Sclerosis

CompletedNCT00848939

United TherapeuticsSystemic Sclerosis

Start: 2008-12-31End: 2010-04-30Updated: 2012-10-23

Effect of Food on the Pharmacokinetics of Oral Treprostinil

CompletedNCT00963001

United TherapeuticsHypertension, Pulmonary, Pulmonary Arterial Hypertension

Start: 2009-09-30End: 2009-11-30Target: 32Updated: 2010-03-08

Effect of Esomeprazole on the Pharmacokinetics of Oral Treprostinil

CompletedNCT00963027

United TherapeuticsHypertension, Pulmonary, Pulmonary Arterial Hypertension

Start: 2009-09-30End: 2009-10-31Target: 30Updated: 2010-03-08

Pharmacokinetic Linearity and Comparative Bioavailability of Treprostinil Diethanolamine

CompletedNCT01153386

United TherapeuticsPulmonary Arterial Hypertension

Start: 2010-07-31End: 2010-08-31Target: 36Updated: 2010-08-23

Comparative Bioavailability of Treprostinil Diethanolamine Manufactured by Two Independent Facilities

CompletedNCT01165476

United TherapeuticsPulmonary Arterial Hypertension

Start: 2010-07-31End: 2010-08-31Updated: 2011-04-19

A Bioavailability Study Comparing Treprostinil Diethanolamine Oral Tablets and Oral Solution in Healthy Volunteers

CompletedNCT01172496

United TherapeuticsPulmonary Arterial Hypertension

Start: 2010-08-31Target: 24Updated: 2010-10-13

Phase 2

Digital Ischemic Lesions in Scleroderma Treated With Oral Treprostinil Diethanolamine

CompletedNCT00775463

United TherapeuticsScleroderma, Systemic Sclerosis

Start: 2009-05-31End: 2011-07-31Updated: 2023-12-28

Open-Label Study of Oral Treprostinil in Digital Ulcers

TerminatedNCT00848107

United TherapeuticsSystemic Sclerosis

Start: 2009-09-30End: 2011-09-30Updated: 2024-06-18

Phase 3

A Pharmacokinetic Substudy of the TDE-PH-304 Protocol

CompletedNCT01934582

United TherapeuticsPulmonary Arterial Hypertension

Start: 2013-08-31End: 2013-11-30Updated: 2024-01-03

Related Papers

Vascular biomarkers and digital ulcerations in systemic sclerosis: results from a randomized controlled trial of oral treprostinil (DISTOL-1).

2019-12-197 citations

Open label study of escalating doses of oral treprostinil diethanolamine in patients with systemic sclerosis and digital ischemia: pharmacokinetics and correlation with digital perfusion.

2013-04-1817 citations